Protein Info for BT4303 in Bacteroides thetaiotaomicron VPI-5482

Annotation: glycogen debranching enzyme-related protein (4-alpha-glucanotransferase) (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 PF12439: GDE_N" amino acids 20 to 240 (221 residues), 269.3 bits, see alignment E=2.3e-84 PF06202: GDE_C" amino acids 285 to 636 (352 residues), 238 bits, see alignment E=1.6e-74

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4303)

Predicted SEED Role

"Putative glycogen debranching enzyme, archaeal type, TIGR01561" in subsystem Glycogen metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89ZS3 at UniProt or InterPro

Protein Sequence (645 amino acids)

>BT4303 glycogen debranching enzyme-related protein (4-alpha-glucanotransferase) (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MSYLRFDKTLMTNLEESLQREILRTNKAGAYHCTTIVDCNTRKYHGLLVIPVPNIDDENH
VLLSSLDETVIQHGAEFNLGLHKYQGNNFSPNGHKYIREFDCEHIPATTYRVGGVVLRKE
KIFVHHENRILIRYTLLDAHSATTLRFRPFLAFRSVREYTHENAQASRDYQLVENGIKTC
MYPGYPELFMQLNKACEFHFQPDWYRGFEYPKEQERGYDFNEDLYVPGYFEVDIKKGESI
VFSAGTSEVTPRRLKQTFEAEVADRTPRDSFYHCLKNSAHQFHNQQEGEHYILAGYPWFK
CRARDMFISLPGLTLALEEVDQFEDVMKTAEKAIRSFINDEPAGYKIYEMEHPDVLLWAV
WALQQYAKETSREQCRQKYGELLKDIIEFIRQRKHENLFLHENGLLYANGTDKAITWMNS
TVNGHPVIPRTGYIVEFNALWYNALRFVADLVREDGNVLLADALDAQAEVTGKSFIEVFR
NEYGYLLDYVDGNMMDWSVRPNMIFAVAFDYSPLDRAQKKQVLDIATKELLTPKGLRTLS
PKSGGYNPNYVGPQIQRDYAYHQGTAWPWLMGFYMEAYLRIYKMSGLSFIERQLIGLEDE
LTIHCISSLPELFDGNPPFKGRGAVSFAMNVAEVLRILKLLSKYY