Protein Info for BT4153 in Bacteroides thetaiotaomicron VPI-5482

Annotation: Exopolygalacturonase precursor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00295: Glyco_hydro_28" amino acids 116 to 318 (203 residues), 79.4 bits, see alignment E=2.8e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4153)

Predicted SEED Role

"Exopolygalacturonase precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A068 at UniProt or InterPro

Protein Sequence (432 amino acids)

>BT4153 Exopolygalacturonase precursor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKQIVGLVLILCCTQMVAQEVFPDGKAIPEWFRENKEVNVNALGKKYSITDYGVANDSTV
VQTKKIQEVIDLAARNGGGVIVIPKGTFLSGSLFFKNNTHLHLEEDAVLKGSDDISHFPV
KMTRMEGQTLKYFMALVNADGLDGFTISGKGTLNGNGLRYWKSFWLRRSINPDCTNMEEM
RPRIIYLSNCKNTQIEGIRIMNSPFWSTHFYKCSFLKLLNLRITSPASPVKAPSTDAVDL
DVCNNVLIKNCYMSVNDDAVALKGGKGPWADKDANNGENYDIIIEDCTYGFCHSAFTCGS
ESILSRNVIVRRCKVDRARALLTLKMRSDTPQKYEYILVEDITGNVQNCLNIAPWTQFYD
LKDRKDTPLSYSNNITMRNIDIDCNVFFNVKKSDQYKLSDFCFENLTVRAKKGKVDQSVI
DSFTMNNVKINQ