Protein Info for BT4115 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF18884: TSP3_bac" amino acids 443 to 464 (22 residues), 23.6 bits, see alignment (E = 1.8e-09)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4115)

Predicted SEED Role

"COG3866 Pectate lyase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A0A6 at UniProt or InterPro

Protein Sequence (497 amino acids)

>BT4115 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MNKKILVGLCALFMLPSIQGNTNTDNSYKENATPDRSKVPAFPGADGAGKYTTGGAGGTV
YTVTSLADDGSEGTFRWAINKKGPRTIVFAVSGIIELQKPLKLSNGDVTIAGQTAPGDGI
CLKNYTFSIQADNVIVRFIRSRMGADIKQKGDDAMNGTKGNSNIIIDHCSLSWCTDECAT
FYDNSQFTLQWCIISESLANSIHEKGAHGYGGIWGGQKASFHHNLLAHHTNRTPRLCGSR
YTGKPEEEKVELFNNVIYNYGSDGAYAGEGGSYNFLNNYYKPGPYSATKGSYRRLFTAYA
DDGKNQNEAGVHGIFHFKGNFMDATCPSLTDKQKEALYKVNMDNTFGLIVKNDFAPEKNL
LSKKAFDIAEHTSLQPAKKAYKDVLQFAGASHRRDAVDQRIVEETRKGNYTYEGSHGSTN
GMVDQPIDVGGWPEYKSEPTPTDSDGDGIPDEWEKKHNLNPNDPSDGAQYSLSKEYTNLE
VYLNELVNHLYPADSKK