Protein Info for BT4114 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1071 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 28 to 1071 (1044 residues), 953.7 bits, see alignment E=1.5e-290 PF13620: CarboxypepD_reg" amino acids 29 to 99 (71 residues), 40.6 bits, see alignment 5.6e-14 PF13715: CarbopepD_reg_2" amino acids 31 to 111 (81 residues), 65.2 bits, see alignment 8.7e-22 PF07715: Plug" amino acids 119 to 225 (107 residues), 63.1 bits, see alignment E=6.6e-21 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 201 to 231 (31 residues), 67.4 bits, see alignment (E = 7.2e-23) PF00593: TonB_dep_Rec" amino acids 409 to 785 (377 residues), 84.3 bits, see alignment E=3.6e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4114)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A0A7 at UniProt or InterPro

Protein Sequence (1071 amino acids)

>BT4114 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MPKGMKNMRTLLLMIFAALSLSVSAQTITLNGNVKDTTGEPIIGASIVEKGNTTNGTITD
LDGNFSLKVPANATVVISYIGMKTQEIAIKGKSKIDVTLSDDAKALDEVVVIGYGTAKRK
DITGSVATVNAEALTVVPVASATEALTGKMAGVQITTTEGSPDAEMKIRVRGGGSITGDN
TPLFIVDGFPVESISDIPASDIEDMTVLKDASSTAIYGSRGANGVILVTTKSGKEGKISV
NYNAYYSWKKMAKQLNTLSSGDYAKWQYELAMLNSGKHDTINPDDYTKVFGNYQDIDLYE
NIEGNNWQDQVFGRTGHTFNHNLSINGGSDKTKFAFSYAHMDDKAIMQDSDFKRDNLSLK
VNHKPNKRVALDFSVRYSNTTINGAGANESKSEVSSADSRMKDVMIYTPFNFKDLSDGYD
PDLQLTNPLVSVADNARQQSRQTFNYNGSFTWEFIDNLKFKTEFGLDHYYNKDKRFYGVT
TYNSRINGNNQPIAVFTSKERKTFRNTNTLNYDFKKILKNKDHSLSLLVGQELIKVKSNT
DTDEVRFYPKLFTADQAFNLSSQGTAFSTDKFYNADDILLSYFARANYDFQGKYLASATF
RADGSSKFSKDNRWGFFPSAALAWRMSSENFMESTKSWLDDLKLRISYGTAGNNNIPSDQ
TSTIWSAGSGASIGWMNNMSSYWTTGAQMANPDLKWETTHTRNAGLDFTLLNGKLSGTVE
YYWNTTKDLLINFPVSGVGYSFQYRNLGETENKGWEVTLNWNAINKKNYALSFNANVGFN
KNKVKSLGSLMDYSADSGWASTDIQSDFKVQPGHSVGEIYGFVSDGRYEVSDFEGFIDGK
WVLKAGVADASDIIGEKYLRPGAMKLKNVDGSEDNKVTKDDQKVIGDTNPFCSGGFSVNA
RVYGFDLTANFTYSIGNDIYNANKIEYTSSSKYKYRNMIDVMAEEKRWTNLNADGTICND
PTQLAAMNANTSMWSPWTQKYVLTDWAVEDGSFLRLATLSIGYTLPQTLTRKVGIQNLRF
YATGYNLFCITNYSGFDPEVSTRTKSALTPGVDYSAYPRSRQYVIGLNLTF