Protein Info for BT3664 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative alpha-glucosidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 638 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF14508: GH97_N" amino acids 32 to 284 (253 residues), 162.2 bits, see alignment E=2.3e-51 PF10566: Glyco_hydro_97" amino acids 289 to 543 (255 residues), 227.1 bits, see alignment E=4.1e-71 PF14509: GH97_C" amino acids 546 to 638 (93 residues), 73.5 bits, see alignment E=2e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3664)

Predicted SEED Role

"Maltodextrin glucosidase (EC 3.2.1.20)" in subsystem Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1J7 at UniProt or InterPro

Protein Sequence (638 amino acids)

>BT3664 putative alpha-glucosidase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKHSFNCLSYELLLYVLICIPFCSCSQKDTGVISPNGKICLSVEIKEDTEKDGFGKVFFN
VEYKDGKTSRRVLSDTRIGLETQLMSFTDNIRLKSVSGTKLIEDDYVMLTGKRSHCQNRG
NERIFRFENEKAETLDIVFRAYDDGIVFRYSLPSVQDKDSLTSEHTAYYIPEGTKRWIQN
YSVGYEGFYPLKTRAERGKDNMWGYPLLLEPADSLFVLITEANILRGHSGSRLYNGNDMN
QYQVRMTDDKLALGDSFTSPWRVLMIGSLSDIVESTLVTDVSEPNKISDTSWIMPGSASW
VYWAHNHGSKNFKIVKDYIDLAVDMKWPYSLIDAEWNEMSNGGDIEDLITYSLSRNIKPM
IWYNSSTAWMGPGPLYRLNSKENRIKEYTWLQKSGVVGVKIDFFPDDYSSNMDYYIDLLE
DAAKYKLMVNFHGATIPRGWQRTYPHLMTMEAVYGAEWYNNKPILTDRAAEHNVTLPFTR
NVIGSMDYTPGTFSDSQHPHITTCGHELALSVVFESALQHMPDRPEVYSSLPRKVREFLS
GLPTAWDDTKLLCGYPGADIVLARRKGDVWYIGGLNGTNENKTLSFSLVPLQVEGKTMDV
FKDGVDDKSFAIEEDIQLSNDKMDMSCLPRGGFVAVIK