Protein Info for BT3661 in Bacteroides thetaiotaomicron VPI-5482

Annotation: alpha-glucosidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 647 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF14508: GH97_N" amino acids 24 to 289 (266 residues), 222.9 bits, see alignment E=6.4e-70 PF10566: Glyco_hydro_97" amino acids 300 to 556 (257 residues), 243 bits, see alignment E=6.2e-76 PF14509: GH97_C" amino acids 558 to 644 (87 residues), 65.1 bits, see alignment E=9e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3661)

Predicted SEED Role

"Beta-xylosidase (EC 3.2.1.37)" in subsystem Xylose utilization (EC 3.2.1.37)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.37

Use Curated BLAST to search for 3.2.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1K0 at UniProt or InterPro

Protein Sequence (647 amino acids)

>BT3661 alpha-glucosidase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKKLVSTLTAILGISTLAAQDVVVKGPDEKLQLAVFVQNETKPCYSVSYNGKTMLEKSPL
GMNTNIGDFTKNLKLTGHSVDKIDTVYQQTRIKVSNVHYRANELTCHLENEQGQKLGVIF
RVSDNDVAFRYTLPHQGGKASVTVKEEQTGFRFPEQTTTFLCPQSDAMIGWKRTKPSYEE
EYKADAPMSDRSQYGHGYTFPCLFRIGNDGWVLVSETGVDSRYCGSRLSDVSEGNLYTVA
FPMAEENNGNGTVAPAFALPGATPWRTITVGDHLKPIVETTVPWDVVSPLYETKHDYRFG
RGTWSWILWQDGSINYDDQVRYIDFASAMGYEYALIDNWWDTRIGHQRMKSLVEYARDKG
VELFLWYSSSGYWNDIEQGPVNRMDNAIIRKREMKWLQSLGVKGIKVDFFGGDKQETMRL
YEDILSDADDHGLMVIFHGCTLPRGWERMYPNYVGSEAVLASENMVFNQHFCDEEAFNTC
LHPFIRNTVGSMEFGGCFLNKRLNRNNDGGTTRRTTDVFQLATTVLLQNPVQNFALAPNN
LKDVPAVCMDFMKRVPTTWDETRFVDGYPGKYVVLARRQGDTWYLAAVNAGKEPLKLKLD
LEMFAGKTVALYKDDKKGEPELTSLKVKENGKVQLEIRPQGGILCIK