Protein Info for BT3599 in Bacteroides thetaiotaomicron VPI-5482

Annotation: beta-mannosidase precursor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 920 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13364: BetaGal_ABD2" amino acids 109 to 184 (76 residues), 27.3 bits, see alignment E=1.3e-09 PF02837: Glyco_hydro_2_N" amino acids 114 to 185 (72 residues), 44.7 bits, see alignment 3.7e-15 PF00703: Glyco_hydro_2" amino acids 248 to 382 (135 residues), 37.1 bits, see alignment E=1.2e-12 PF18368: Ig_GlcNase" amino acids 816 to 917 (102 residues), 74.6 bits, see alignment E=1.7e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3599)

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.25

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1R0 at UniProt or InterPro

Protein Sequence (920 amino acids)

>BT3599 beta-mannosidase precursor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKKLLILYPFLLFCLISKADNQLKLTNWEIKSTTEISENAEKVSMPSFQATDWYEATVPT
TVLNALVKQNVYPDPRIGMNNFLIPDVSDEFNKKMDLAKYSYLGNGKNPWQEPYWYRTTF
TLPKQYKNKKIWLNLNGINYRADVWINGHQIGKKEDVVGMFRRFKFDITDYIQPTQNCIA
IKIYQVDHPGTPNPGTQFIAFGPNRGTASDLFKDETLKFTGGWDCAPVVRDRNMGIYQSV
TLEATSQVTIEDPYIITTLPQKDTTVADITIKATVHNHSDKMISGKVKATIRLINELVYP
SYTRKLAGSMKPISVTLPVTMLPNESKEIILSPQKFSVLSIQNPYLWYPNGYGEQYMHSL
DLSFDMNNGKSSDREKVNFGIREVTSELMKNGEEYGRVFFINGKRIFCKGGWIQPDVLLD
DSPKRIYDQARLMANANITLIGSEDMPSPSEDWLDSWDKYGLMNWHVFYQCYRMFPGRDN
QHNPLNNDLAIACVKDMVKRYRNHPCIIAWFGVNEVLVDEELYHPTKEAVLSLDTTRPYI
PTTSISWDVDKLTPYLKPDLPTGTTDDGAPDYNWAPSDYYFDKVEEVYLQMFRNELGMPS
VPVYESLKKFIPTIDKPLDRRNPIYPLDSIWAEHGAWDTNNFCYRAYDNAIRTFYSDPVS
SEDYAYKGQLVSSEGYRAMFEAANHRMWDITTGIMIWKLNSCWPDVCWQIYDWYLSPNAS
YYFSKKAMEPIHIQMNANTNRISVINATHQEFKSVIAKARIIDYSMKECWAYTDTISVGA
DQYKELETVPQRGDLSAIYYIKLELEDLNRNLISENLYWRYSQHQNFYWLVNMPKVTLKQ
DLKLQKQEKEYQITLTLTNDSDKLSFFNHLMIQREKTKEVVNPVFWSDNFISLFPNETRT
ITATVSIEDLHGENPIIIIK