Protein Info for BT3565 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative TonB-dependent receptor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 853 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF07715: Plug" amino acids 146 to 231 (86 residues), 32.6 bits, see alignment E=1.5e-11 PF00593: TonB_dep_Rec_b-barrel" amino acids 342 to 762 (421 residues), 72.4 bits, see alignment E=1e-23 PF14905: OMP_b-brl_3" amino acids 390 to 816 (427 residues), 259.2 bits, see alignment E=1e-80

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3565)

Predicted SEED Role

"putative TonB-dependent receptor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1U3 at UniProt or InterPro

Protein Sequence (853 amino acids)

>BT3565 putative TonB-dependent receptor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKHRLLLLLLFVFTAVMTGWAQNSAMPSYTVKGVLLDSLTQDGEPYATIKITKKGAPDKA
VKMAVTGANGRFQEKLNVGAGDYVITISSIGKAPVTKEFTLKPSVRVIDLGTMLSAEANN
ELKGVEVVAQKPLVKVDVDKIEYNIEDDPDSKSNSILEMLRKVPLVTVDGEDNIQVNGSS
SFKIHVNGKPNNMMSNNPKEVLKSMPANSIKYIEVITSPGAKYDAEGVGGILNIVTVGGG
FEGYTATFRANASNYGAGAGGYAMVKQGKMTVSANYNFNYNDRPRGYSDSYRENYESDTE
KYLESNSSSKSKGNFQYGNLEGSYEIDTLRLLTVAFGMYGSNSKNYGDGFTTMYGANHED
IAYSYRTGNHGDGSWYSINGNIDYQRTSRKNKQRMITFSYKINTQPQTSNSNTGYEDIHA
KEEVDDLVKRLLLKNSQSDGKTNTMEQTFQVDYTTPIGELHTVEAGAKYIFRRNTSDNKL
YEAAGGSDDYLYNEDRSSDYRHLNHILAAYLGYTLKYKDFTFKPGVRYEQTVQRVKYIVG
PGENFHTNFSDLVPSVSLGMKLGKTQNMRVGYNMRIWRPGIWNLNPYFNNLNPMFITQGN
SNLKSEKSHAFDLSYSNFSAKFNINVSLRHSFNNNSIENISRLITAPEGEMFDNDPTHIA
PEGALYSTYANIGKSRNTGMSLYLNWNASPKTRLYVNGRGNYSDLKSEAQGLHNYGWNGS
FYGGVQHTLPLKIRLSLNGGGSTPYINLQGKGSGYYYYSLGASRSFLKDERLSLNVYCSN
IFEKYRSYNNHTEGVNFLSKSSSKWPSRSFGVSISYRIGELKASVKKAARSINNDDVKGG
GGEGGNTGGGGGQ