Protein Info for BT3551 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative zinc protease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1030 transmembrane" amino acids 24 to 41 (18 residues), see Phobius details amino acids 62 to 78 (17 residues), see Phobius details PF00675: Peptidase_M16" amino acids 113 to 161 (49 residues), 28.8 bits, see alignment 1.1e-10 PF05193: Peptidase_M16_C" amino acids 314 to 484 (171 residues), 87.4 bits, see alignment E=1.2e-28 amino acids 821 to 936 (116 residues), 24 bits, see alignment E=3.2e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3551)

Predicted SEED Role

"peptidase M16 domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1V7 at UniProt or InterPro

Protein Sequence (1030 amino acids)

>BT3551 putative zinc protease (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MSKIPPQRISALFHVFKLFNSNHVIYNFIIYNLQISLFGAKVRKIPLPLFLSLKCCHNMN
KLLKLSCLSLFLALVMSSCSSQKKYSYETVPNDPLKARIYTLDNGLKVYLTVNKETPRIQ
TFIAVRVGGKNDPAETTGLAHYFEHLMFKGTDKYGTQDYAAEKPLLDQIEQQFEIYRQTT
DEAERKAIYHTIDSLSYEASKYAIPNEYDKLMAAIGSSGSNAYTWYDQTVYQEDIPSNQI
ENWAKIQADRFENNVIRGFHTELEAVYEEKNMSLTRDNSKVQEAIFSSLFPKHPYGTQTV
LGTQENLKNPSITNIKNYYKQWYVPNNMAICMSGDLDPDETIALIDKYFGGLKPNPELPK
LNLPKEDPITAPVVKEVLGPDAESVALAWRFPGLASKDFEVLQVVSQVLYNGKAGLIDLD
LNQQQKVLNSYGYPMGLADYSAFILGGLPKQGQTLEEVKDLLLNEIKKLRAGEFDEKMLQ
ANINNFKLYELQSMESNEGRADIFVNSFINGTNWEDEVTAIDRMAKLTKEDIVAFADKYL
KEDNYAVVYKKQGKDPNEKKMTKPEITPIVSNRDVASPFLTSIQESAVKPVEPVFLDFKK
DMSQLTAKSDIPVLYKQNVTNDLFQLIYVFDMGNNNDKALGTAFDYLEYLGTSDMTPEEL
KSEFYRLACTFYVSPGNERTYVVLSGLNENMPAAMQLFEKLLADAQVNKEAYDNLVGDIL
KARADAKLNQGQNFSRLMNYAMYGPKSPATNLLTEAELASMNPQELVDRIHNQNNYKHRI
LYYGPSSSKDLLATIEQYHQVPATLKDIPAGNEYSYLETPATKVLVAPYEAKQIYMAQIS
NLDKKYDPAIEPTRELYNEYFGGGMNSIVFQEMCETRGLAYSAWAGIMPPSYLKYPYTIR
TQIATQNDKMIDAVNTFNDIINNMPESEAAFKLAKEGLINRMRTDRIIKSDIIWTYINAQ
DLGQSVDPRIKLYNDVQTMTLKDIVDFQKEWVKGRTYVYCILGDKKDLDMNKLKAVGPIE
ELTQEQIFGY