Protein Info for BT3475 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1039 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 26 to 1039 (1014 residues), 1108.4 bits, see alignment E=0 PF13620: CarboxypepD_reg" amino acids 27 to 96 (70 residues), 36.7 bits, see alignment 6.6e-13 PF13715: CarbopepD_reg_2" amino acids 27 to 109 (83 residues), 52.3 bits, see alignment E=7e-18 PF07715: Plug" amino acids 117 to 222 (106 residues), 67 bits, see alignment E=2.9e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 198 to 228 (31 residues), 66 bits, see alignment (E = 2e-22)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3475)

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A231 at UniProt or InterPro

Protein Sequence (1039 amino acids)

>BT3475 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MMKNFLFICMLLLGLSTSALAQESIVVTGVVTDTNKEPMIGVNVSISNIPGLGAITDLNG
KYSIKMPPYHKLVFTYIGFEKVEVLVKEQRTVNVTMKEASAREIDEVVITGTGAQKKLTV
TGAITNVDVDVLKANPSGSMANALAGNVPGILAMQTSGKPGSVSEFWIRGISTFGASNSA
LVLVDGFERSLDEINVEDVESFSVLKDASATAIYGSKGANGVVLITTKHGKAGKINISAK
AETFYNMLTQVPDFVDGYTYASMANEAKITRNLEPLYKADELEIFRLGLDPDLYPNVNWI
DELLRKGSWSTRATLSMNGGGNTARYYVSGSYLDQQGMYKVDKALKDYNTNANFRRWNYR
MNVDIDITKSTLLKVGVSGSLQKANDSGVGSDAIWTALMGYNAIMVPKLYSNGYVPAYGN
DNGDRFNPWVQATMTGYRENWKNNIQTNVTLEQKLDFITKGLRFVGRFGYDTENNNWINR
RKWPEQWKAKRFRATDGTLDYDRVAEERKMFQESGSDGLRNEFFEAELHYSRGFKHHHLG
GTLKYNQSSKIKTVGLGDDLKQGIARRNQGLAGRFTYNWNYRYFIDFNFGYTGSENFAAG
HRFGFFPAISGAWNIAEESLIKKHLKWMNMFKIRYSYGKVGNDNLGNTRFPYLYDIETMT
KKDGDKTVDTGGYNFGDYTFDRYYGGMRYSSLSSPNVTWEIATKHDLGIDFSFFNDKLSG
SVDYFNEKREGIYMLREYLPGIVGLESNPSANVGKVTSEGFDGHFTFRQKLGAVGLTIRS
NITYSKNEIVDRDEENNYYWYKMQKGHRVNQARGLISLGLFKDYDDIRNSPVQDFDGYKV
MPGDIKYKDVNGDGKIDGNDQVAIGATTKPNLIYGFGIAANWKGLDVNLHFQGAGKSTYF
IDGSTVHMFKLGDGWGNVLSEMANSNRWISADISGDPATENPNAEYPRLSYGPNSNNYQQ
STYWLRNGSYLRLKTVEVGYTLPTQLVNKVHFNTVRIFFVGTNLLTWSAFKLWDPEMGST
DGKRYPLSKNLSLGISVNL