Protein Info for BT3376 in Bacteroides thetaiotaomicron VPI-5482

Annotation: nucleotide sugar transaminase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 PF01041: DegT_DnrJ_EryC1" amino acids 22 to 367 (346 residues), 327.5 bits, see alignment E=1.2e-101 PF00155: Aminotran_1_2" amino acids 36 to 163 (128 residues), 25.1 bits, see alignment E=1e-09

Best Hits

Swiss-Prot: 54% identical to VIOA_SHIDY: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (vioA) from Shigella dysenteriae

KEGG orthology group: None (inferred from 100% identity to bth:BT_3376)

Predicted SEED Role

"Aminotransferase, DegT/DnrJ/EryC1/StrS family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A2C9 at UniProt or InterPro

Protein Sequence (369 amino acids)

>BT3376 nucleotide sugar transaminase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MIDKPIYVTSPLLPSLEDFTFLLKEIWESKMLTNNGNFHQKLEEELAKYLKVPYLSLFTN
GTLPLITALQAMRITGEVITTPFSFVATTHSLWWNGIKPVFVDIEPETCNLDPSKIEAAI
TPRTTAIMPVHVYGKPCKTKEIQEIANKYGLKVIYDAAHAFGVEINGESILNFGDMATLS
FHATKVYNTLEGGALVVHDEQTKKRIDYLKNFGFASETEVVAPGINSKVDEVRAAYGLLN
LKQVDHAINSRRKVAIRYRDELQGVKGITFFNDIPGVRHNYSYFPIFINAEEYGMTRDEL
YFKMKEHNVFGRRYFYPLISTFSTYRGLDSANPDNLPIATQMSNNVICLPMHHALSENEV
EYILQIIKK