Protein Info for BT3352 in Bacteroides thetaiotaomicron VPI-5482

Annotation: haloacid dehalogenase-like hydrolase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 TIGR01484: HAD hydrolase, family IIB" amino acids 5 to 236 (232 residues), 92.3 bits, see alignment E=4.6e-30 TIGR00099: Cof-like hydrolase" amino acids 5 to 263 (259 residues), 197.7 bits, see alignment E=2.5e-62 PF08282: Hydrolase_3" amino acids 6 to 263 (258 residues), 240.6 bits, see alignment E=6e-75 PF05116: S6PP" amino acids 178 to 243 (66 residues), 29.6 bits, see alignment E=1.4e-10

Best Hits

KEGG orthology group: K07024, (no description) (inferred from 100% identity to bth:BT_3352)

Predicted SEED Role

"Haloacid dehalogenase-like hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A2F3 at UniProt or InterPro

Protein Sequence (270 amino acids)

>BT3352 haloacid dehalogenase-like hydrolase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKYKLIVLDLDGTLTNSKKEISSRNRETLIRIQEQGIRLVLASGRPTYGIVPLANELRMN
EFGGFILSYNGGEIINWESKEMMYENVLPNEVVPVLYECARTNHLSILTYDGAEIVTENS
LDPYVQKEAFLNKMAIRETNDFLTDITLPVAKCLIVGDAGKLIPVESELCIRLQGKINVF
RSEPYFLELVPQGIDKALSLSVLLENIGMTREEVIAIGDGYNDLSMIKFAGMGVAMGNAQ
EPVKKAADYITLTNDEDGVAEAIERIFNVP