Protein Info for BT3072 in Bacteroides thetaiotaomicron VPI-5482

Annotation: collagenase precursor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 PF01136: Peptidase_U32" amino acids 81 to 311 (231 residues), 225.2 bits, see alignment E=3.5e-71

Best Hits

KEGG orthology group: K08303, putative protease [EC: 3.4.-.-] (inferred from 100% identity to bth:BT_3072)

Predicted SEED Role

"Collagenase precursor (EC 3.4.-.-)" (EC 3.4.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A383 at UniProt or InterPro

Protein Sequence (427 amino acids)

>BT3072 collagenase precursor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MNIKDFEIMAPVGSRESLAAAIQAGADSIYFGIENLNMRARSANTFTVDDLREIAQTCDE
HGMKSYLTVNTIIYDKDIPLMRTIVDAAKAAGISAVIAADVAVMNYARQIGQEVHLSTQL
NISNAEALKFYAQFADVVVLARELNLEQVAEIYRQIREENICGPSGEQIRIEMFCHGALC
MAVSGKCYLSLHEMNHSANRGACMQVCRRSYTVRDKETDVELDIDNEYIMSPKDLKTIHF
MNKMMDAGVRVFKIEGRARGPEYVRTVVECYKEAIKAYLDDTFTDEKIAAWDERLKAVFN
RGFWDGYYLGQRLGEWTRNYGSAATERKIYVGKGIKYFSNIGVSEFLVEAAEVSVGDKLL
ITGPTTGAVFMTLDEARVDLKPVETVKKGQRFSMKSEKIRPSDKLYKLVSTEELKKFKGL
DVEQKRG