Protein Info for BT2970 in Bacteroides thetaiotaomicron VPI-5482

Annotation: alpha-L-fucosidase precursor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01120: Alpha_L_fucos
  • amino acids 29 to 379 (351 residues), 289.2 bits, E=3.1e-90

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2970)

Predicted SEED Role

"Alpha-L-fucosidase (EC 3.2.1.51)" in subsystem L-fucose utilization or L-fucose utilization temp (EC 3.2.1.51)

MetaCyc Pathways

• xyloglucan degradation II (exoglucanase) (5/8 steps found)

KEGG Metabolic Maps

• Other glycan degradation

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.51

Use Curated BLAST to search for 3.2.1.51

Sequence Analysis Tools

See Q8A3I4 at UniProt or InterPro

Protein Sequence (484 amino acids)

>BT2970 alpha-L-fucosidase precursor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKNTIIYRMKSRLITLLLLLITVSSVTFAQEAKKEIPLKYGATNEGKRQDPAMQKFRDNR
LGAFIHWGLYAIPGGEWNGKVYGGAAEWLKSWAKVPADEWLKLMDQWNPTKFDAKKWAKM
AKEMGTKYVKITTKHHEGFCLWPSKYTKYTVANTPYKRDILGELVKAYNDEGIDVHFYFS
VMDWSNPDYRYDIKSKEDSIAFSRFLEFTDNQLKELATRYPTVKDFWFDGTWDASVKKNG
WWTAHAEQMLKELVPGVAINSRLRADDKGKRHFDSNGRLMGDYESGYERRLPDPVKDLKV
TQWDWEACMTIPENQWGYHKDWSLSYVKTPIEVIDRIVHAVSMGGNMVVNFGPQADGDFR
PEEKAMATAIGKWMNRYGKAVYACDYAGFEKQDWGYYTRGKNDEVYMVVFNQPYSERLIV
KTPKGITVEKATLLTTGEDITVVETTRNEYNVSVPKKNPGEPYVIQLKVRAAKGTKSIYR
DALT