Protein Info for BT2920 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1064 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 51 to 1064 (1014 residues), 1026.7 bits, see alignment E=0 PF13620: CarboxypepD_reg" amino acids 51 to 118 (68 residues), 38.6 bits, see alignment 1.8e-13 PF13715: CarbopepD_reg_2" amino acids 52 to 133 (82 residues), 60.1 bits, see alignment 2.5e-20 PF07715: Plug" amino acids 141 to 249 (109 residues), 57.2 bits, see alignment E=3.5e-19 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 225 to 255 (31 residues), 58.8 bits, see alignment (E = 3.4e-20)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2920)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A3N4 at UniProt or InterPro

Protein Sequence (1064 amino acids)

>BT2920 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKTKTRDLSACLKRRLWIAGVCLAAFSFLSVSVVYAADDIQTIQQQKKGMTIKGKVLGTD
GEPIIGASVLVKGSTTGVVTDLDGNYTLANVSKGAILEFSYVGYVKLTKTVGSETTINAI
LYEDSQMLEGVEVVAFGTQKKESVIGAISTVKVAELKTPSSNLTNALAGRIAGVISYQRT
GEPGVDDASFFVRGVTTFGYKKDPLILIDGIELTSTDLARLQPDDIASFSIMKDATATAL
YGARGANGVILVKTKEGQKGKARLSLRVENSISAPTQEIDLADPVTYMRLHNEAYLTRNP
LAPLMYSEEKIDNTVPGSGSVIYPATDWRKELLKDFTMNQRVNLNITGGGDVARYYVAAS
YSQDNGILEVDKNSNFNNNIKQRVYTLRSNVNINATKTTELIVRLSGVFDDYNGPLYGGS
AMYNLIMKSNPVLFPAKYPKDEAHAYTKHTLFGNAENGQYLNPYAEMVRGYKESGRSNLS
AQFEVKQDLKFLTEGLSARLLFNTSRISSYDVSRKLNPYYYKMTNYDYLTGDYAIDIINP
DEGSEYLIYDPGGKSITANMYIEAALNYNRDFGKHGVGGLLVYQLRNNLQPNAGSLQASL
PYRNVGLSGRFTYAYNNRYFAEFNFGYNGSERFHKSKRFGFFPSAGLAWVVSNESFWDPF
KSVVSKLKLRASYGIVGNDAIGSGRFLYLSDINMNDSKYGANFGYNFDYHRDGISVKRYS
DPEITWEKSAKTNFALEFTLFDDLNVTAEYYTERRKSILQQRASIPASMGLWVQPYANLG
EAKGSGVDLSLDYNKYFANKSWLQLRGNFTYATSEYMVYEDYEYPGAWWKQKVGYPTNQT
WGYIAEGLFVDDNEVANSPVQFGEYGAGDIKYRDVNKDGKITDLDQVPIGYPKEPEIVYG
FGASYGYKNWDISVFFQGLARESFWIDYNNVSPYFNTVDTKVVGNRVGHNALAKFIADSH
WSEDNRDAYAVWPRLSPTSIENNSKTSTWFMRDGSFLRLKQLEIGYTIPEKVTNKVGIKN
LRFYVTGNNLLCFSKFKLWDPEMAGAGLGYPVQRVYNVGLNLTF