Protein Info for BT2894 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1018 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 30 to 1017 (988 residues), 1070.4 bits, see alignment E=0 PF13620: CarboxypepD_reg" amino acids 30 to 99 (70 residues), 38.7 bits, see alignment 1.6e-13 PF13715: CarbopepD_reg_2" amino acids 31 to 111 (81 residues), 63.6 bits, see alignment E=2.1e-21 PF07715: Plug" amino acids 119 to 224 (106 residues), 66.2 bits, see alignment E=5.4e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 200 to 230 (31 residues), 65 bits, see alignment (E = 4.1e-22)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2894)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A3R0 at UniProt or InterPro

Protein Sequence (1018 amino acids)

>BT2894 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MSKRLLNYVIVLLVCLISSAESFAQGTKFQVKGNVTDASREPIVGATIKVKGTSQGVITN
IDGEYSIDTRSNAILEFSYIGYVSQEVPVSGSKIINVTLQEEVSKLDEVVVVGYGTQKKI
SVTGSVSNVSTKEIAKIATPSLSNTLGGQIPGIVTRQATGEPGYDQASIYIRGFGTWTNR
SPLILVDGIERDMNTINTEEVESISVLKDASATAVYGVRGANGVILITTKRGQLGKPKVT
LRSEYAVLTGLRYPEYINAAEYAGLMNEARDNAGVANMAYTDEEIELFRNGSSPYLYPNV
NWVDEVLKKNTTQSITNLNITGGTEVVRYFVNVGYTTQSGLYRDNGDNAYSTNSRVNRYN
YRSRVDVNLTKDLSVELGVGGIIQNRNFPGKSQYDIFYAIRNTSPLAFPVKNPDGTPGAS
PTYLGNNPWGMTTQSGYETQNWNTLQGTFSARWDLSSLVTEGLSVSGRFAYDHYYSNNKQ
YYKDFEVKQYMGEDAEGNAIYNILRNENIKNVTLAESANRAIYYEVAANYDRTFGMHNIT
GMFLFNRRDYVNLRNTDRTGSVPYRRQGIAGRASYNYLQRYFAEFNFGYNGSEQFPKGKR
YGFFPSVSLGYVLTNEDFWNRNWWISNLKLRGSYGTVGNDISSSTRFLYLTTMNMNVSAG
YMGKEGNNYMAGIMEGQTGNQNVTWETAKKLNVGFDLGLFNDVVSLQVDIFKEKRDGILI
TRKTVPVLAGFSGASIPVGNLGKAENKGIETALEVKKRVANGLFYSLRGNFSFARNKIIE
NDEPKPKYEYQDARGRRIDQTFGLVALGFFKDQDDIKNSPKQTFQSTVRPGDIKYKDING
DGVVDEYDKVAIGDPRTPEIMFGFGGTVAYKNFDVSLFFTGAAKTSFFLEGATVYPFLNG
EGTWNVLREVYDNRWTSETAATAKYPIVLNANSYNNYQTSTMYMRNGSYLRLKSAEIGYT
FKGRLIDKMFMDNIRLFCNGQNLLTLDYIKIVDPESNNGVGNYPMQRTINFGFQINFK