Protein Info for BT2626 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1034 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 26 to 1034 (1009 residues), 1038.9 bits, see alignment E=0 PF13715: CarbopepD_reg_2" amino acids 28 to 108 (81 residues), 58.3 bits, see alignment 9.6e-20 PF07715: Plug" amino acids 119 to 222 (104 residues), 50.2 bits, see alignment E=5.2e-17 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 198 to 228 (31 residues), 64.7 bits, see alignment (E = 4.8e-22)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2626)

MetaCyc: 100% identical to SusC-like TonB-dependent receptor monomer (Bacteroides thetaiotaomicron)
RXN-23727; TRANS-RXN-1546

Predicted SEED Role

No annotation

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A4H3 at UniProt or InterPro

Protein Sequence (1034 amino acids)

>BT2626 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKVKYALVLLSLLISSMELFAQEVIDLKGCVYDEQKTPVPGAAVYLKDRPGVGVSTDIDG
EFSIKATIGDILVVSFIGYKTQEKLITKQEKIIITLSPETEELEEVVITGLGTSQRKVSL
VGAITNVDMNQIKAPSASINNMLGGRVAGIISQQYSGEPGKNVSEFWVRGIGTFGANSGA
LVLIDGLEGDLSMVDPADVESFSILKDASATAVYGVRGANGVVLITTKRGTTEKLQVTAR
ANFTISKLTRMPEYLQAYEYAQLANEAKIVRGDLPLYDDIALYAIKHQLDPDLYPDVNWR
DETLNKTSFKHTYYASARGGGSVAKYFLSLGMSKEDAAYKIDKNSKYNKGLGYNKFTYRS
NIDMNLTKTTNLYFGMEGWFTVNKEPGNSEQNATDAVWNAQALLTPLTIPTKYSTGQLPS
YGTLNAYSPYVMINHTGKKQTENSNNQITLALNQDLSFITKGLKIRAQGAITRNTNYSER
RYVLPEMYYATGRYANGQLQLVKKQDEVKAQFSNYQNQYSKYHFESTLNYERLFGTDHRF
SALVYYYMSSEKNLQDIANADSNFETMAAIPKRYQGVSSRVTYGFRDTYLMDLNFGYTGS
ENFQPGKQFGFFPSFAFGWIPTQYDIVKEKFPWLDHLKLRGSYGLVGNDRITDKRFPYLT
IVNSGAPLGWGGNVGGGISESVIGADNLEWEKSKKLDIGIEGKLFNNKIDFVMDYFWDKR
EGIFQQRAQIPNFVGLVSLPYGNVGQMKSWGADGNISYTQQINKDMSFVIRGNFTYSKNK
IDNWEQIEQKYAYQNFSGWPYGIQRGYIALGLFRDEADINNSPIQTFGNYEAGDIKYKDV
NGDGRIDIDDQVPLSYDNYPRLMYGFGGEFRYKNLTFNILFKGIGKKDFFYTSEDSGFGY
YPFLYGETGNVLSIVANSSNRWIPASYSGDPSTENPNARFPRLSYGKNSNNTQKSTFWKA
NGQYLRLQEISVGYNLKLKAFSKIGVSSIDLQLVGQDLYVWDKIGGLWDPEQTTKNGRAY
PIPATYSLQMYINF