Protein Info for BT2566 in Bacteroides thetaiotaomicron VPI-5482

Annotation: HIT family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 130 PF11969: DcpS_C" amino acids 3 to 105 (103 residues), 45.7 bits, see alignment E=1.3e-15 PF01230: HIT" amino acids 11 to 100 (90 residues), 74.1 bits, see alignment E=1.8e-24 PF04677: CwfJ_C_1" amino acids 23 to 104 (82 residues), 27.1 bits, see alignment E=4.9e-10

Best Hits

KEGG orthology group: K02503, Hit-like protein involved in cell-cycle regulation (inferred from 100% identity to bth:BT_2566)

Predicted SEED Role

"HIT family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A4N3 at UniProt or InterPro

Protein Sequence (130 amino acids)

>BT2566 HIT family protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MATIFSRIIAGEIPCYKIAENDRFFAFLDINPLVKGHTLVVPKQEVDYIFDLSDEDLAAM
HVFAKKIARAIEKAFPCKKVGEAVIGLEVPHAHIHLIPIQKESDMLFSNPKLKLSDEEFK
SIAQAISSSL