Protein Info for BT2439 in Bacteroides thetaiotaomicron VPI-5482

Annotation: beta-N-acetylglucosaminidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1001 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00933: Glyco_hydro_3" amino acids 53 to 366 (314 residues), 239.8 bits, see alignment E=5.4e-75 PF00144: Beta-lactamase" amino acids 598 to 980 (383 residues), 163.9 bits, see alignment E=5.8e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2439)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A508 at UniProt or InterPro

Protein Sequence (1001 amino acids)

>BT2439 beta-N-acetylglucosaminidase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MRLLTYILAILLFLPVKARGEAIDTPVEPLLLYKAKQDVRCQQWVDSIMNKLTLKEKVGQ
LFIYTIAPVDTKRNQILLKDAVDTYKVGGLLFSGGKMQTQAELTNRAQRMAKLPLMITFD
GEWGLAMRLRGTPVFPRNMVLGCIQDNKLIYEYGREMARQCVQLGVQVNFAPVADVNINP
KNPVINTRSFGEDPVRVADKVVAYASGLEGGGVLSVCKHFPGHGDTDVDSHKTLPVLPFT
RERLDSVELHPFKEAIRAGLSGMMVGHLQVPVIEPIGGLPSSLSRNIVYDLLTEEFAFKG
LIFTDALAMKGVSGNGNVSLQALKAGNDMVLAPRNLKEEIAAVLDAIDKGELTREDIEEK
CRKVLTYKYVLGLKKKPFVQLSGLGQRINTPQTRDLIRRLNLAAITVLNNENHVLPLHTN
QKETMALLEVGDAGETNALAEQLSKYTSLSRFRLRPGMTEEANQRLRDSLATYKRIIVAV
SEQKLSPYQTFFGKFTTEAPVIYAFFTQGKMMLQIQRAVARASAVVLGHSPNEDVQRQVA
DVLFAKATADGRLSASLGELFQAGDGVTITPKTPLHFIPEEHGLSSVALQRIDSIALDGV
RQGAYPGCQVIVMKEGHVMVDKTFGTHTGTGSARVQPTDIYDLASLSKTTGTVLALMKLY
DKGRFNLTDRIADYLPFLQRTNKKDITIQELLYHQSGLPPGIAFYREAIDEDSYEGRLFM
SRKDARHPLQLGTSTWANPNFAFKKEYVSKVKTGDYTLQICDSLWLNPSFFKEMEKKIAD
APMKPKTYRYSDVGFILLRLLVEKLAGMPMDAYLQREFYEPMGLERTGYLPLRRFPKSEV
VPSSVDRFLRKTTLQGFVHDEAAAFQGGVSGNAGLFSNAREVAQVYQMLLNGGELNGQRY
LSKETCQLFTTEVSKISRRGLGFDKPDTRNPEKSPCGKHTPAKVYGHTGFTGTCAWVDPD
NGLVYVFLSNRIYPDVTNRKLSRLEIREQIQDAIYKAIQSK