Protein Info for BT2390 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 743 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07715: Plug" amino acids 45 to 153 (109 residues), 42.3 bits, see alignment E=1.5e-14 PF00593: TonB_dep_Rec" amino acids 265 to 699 (435 residues), 111.5 bits, see alignment E=1.5e-35 PF14905: OMP_b-brl_3" amino acids 499 to 707 (209 residues), 29.3 bits, see alignment E=7.1e-11

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to bth:BT_2390)

Predicted SEED Role

"Thiamin-regulated outer membrane receptor Omr1" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A552 at UniProt or InterPro

Protein Sequence (743 amino acids)

>BT2390 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKKMMMMAVALLGAGFPVHAQTSAKDSLKVINLQEVQVVSTRATAKTPVAFTNIGKAELK
KVNFGQDIPYLLSMTPSTLTTSDAGSGIGYTTLRVRGTDGTRINITVNGIPMNDAESHNL
FWVNMPDFSSSVKDMQVQRGAGTSTNGAGAFGASVNMQTEGASMKPYAEFNGSYGSFNTH
KETVKVGTGLLNNHWTFDARLSNIGTDGYIDRASVNLNSYYLQGGYFAENTSVKLIAFAG
KEKTYHAWGYATKAEMEEHGRRYNPCGEYTGDDNEKHYYADQTDNYLQKNYQLLFNHTFS
TAWNLNVALHYTKGDGYYEEYKEDRSFLEYGLKPFTTDGKEISESDLVRQKKMDNKFGGG
VFSLNYTNHRLTASLGGGINQYRGNNFGKVTWVKNYIGALSPDHEYYRNQSKKTDGNIYL
KASYDLTGGLSAYADLQYRHIDYTIDGANDKYDWNKNALRPLAVDKKFDFFNPKVGLNWN
INSNHRVYASFSVAQKEPTRNNYTDGNPDSYPKAEKLLDYEAGYTFANHWLTAGANFYYM
DYTDQLVLTGALNDIGEALTENVPNSYRMGIELMLGIKPCKWFQWDINATWSKNRIKNFV
ENIPIYDGWNLLDIVSVSHKSTRIAFSPDFLLNNRFAFTYQGFEAALQSQFVGKQYMTNA
EVEALTLDKYFVSNLNLAYTFKPRKVVKEVTLGVTVYNLFNEEYENNGWASSSYDKDVNH
RINSAGYAAQAGTNVMGHVSFRF