Protein Info for BT2364 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1025 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 29 to 1025 (997 residues), 897 bits, see alignment E=2.1e-273 PF13620: CarboxypepD_reg" amino acids 30 to 91 (62 residues), 42.1 bits, see alignment 1.9e-14 PF13715: CarbopepD_reg_2" amino acids 30 to 114 (85 residues), 71.7 bits, see alignment E=8.2e-24 PF07715: Plug" amino acids 122 to 248 (127 residues), 68.8 bits, see alignment E=1.1e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 224 to 254 (31 residues), 60.6 bits, see alignment (E = 9.3e-21) PF00593: TonB_dep_Rec" amino acids 443 to 988 (546 residues), 39.8 bits, see alignment E=1.1e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2364)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A578 at UniProt or InterPro

Protein Sequence (1025 amino acids)

>BT2364 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKINQRLTLCFSLLFCLLSISYASAQQLNISGVVISSEDNEPLIGATVSVKGNPTKGVIT
DINGQFQLSVETGTKLLVVSYVGMKTQEIRVPRKEKELKIVLIPETMDIDEVVVTGYGNF
SKSSFTGSANTLRTDMLKEVPVMSVEQKLQGMTTGVQITSSSGQPGANQSIRIRGMGSFN
ASQEPLFVIDGVPVTSGSMSSGGPDAAYMNNSKTNIMSTLNPSDIENVTVIKDAAAASLY
GSRAANGVILITTKKGNTGKVRVDLNVSGGFSHAAVDFRPTLNGDQREELLYEGLLNYAT
DNGMESPTEYASSNIGTYAYKPAMGYTDWRKELLRTAMHQSYEASVSGGNDRSTFYASLG
YNNQEGLAKNSSLDRYSARLNVTQKVGKYGEVGANMMFSQMNQEMNEERGSSINPFLCVA
MTMTPSMVVRDEEGNYVGAYDGTSLNPLRDILTDYNRVRMTRMFSTGYAAIEPIKGLKLK
ETLSYDYTIQKDSRYYNPLSSAGPKSGSDAQTAKGFIEYGKLISSTSLNYVRTFARKHHL
DVLAAYEIESYQTDHASGEKSKLPSDKLTEPDNAAVLNSFKSATQAYRMISYLSRLNYDY
DDRYYIAGSYRRDGSSRLSPNNRWGNFWSVSGMWHLGNENFMKAVKPVLSDVKIRASYGV
NGNQPGSYYGYKGLYSYGENYMEAAGSYESAQPNDLLTWEKNYSLNLGIDLSFINRIFAS
LEYYNRDTKDLLYSLPISATTGFTSYLSNIGRLNNKGVEFELRTLNVVSNDFNWTSVFNL
SHNRNKIVSLNGLLDQTIEGTWFIHKVGLPYHTFYVKEFAGVDPLTGSAQYYLNTKNEDG
SYNRELTTDAAKAESIPYKTATPKVSGGFTNILNYKWIDLTFTLTYSLGGYSFDKLGTYI
ENGSSSIYSSRYNLPAYMMNRWQKPGDQTDIPRFVYGEPATSTNSSRYIHSTDHLRLKNF
TLGFTLPNQWTQKLMIDKVRVYFSGNNLLTWAKWKQYDPETPVNGEVFCEAPAMRTFSFG
AQLSF