Protein Info for BT2311 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 PF01507: PAPS_reduct" amino acids 27 to 227 (201 residues), 48.1 bits, see alignment E=1.4e-16 PF11922: DUF3440" amino acids 230 to 409 (180 residues), 299.4 bits, see alignment E=8.8e-94

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2311)

Predicted SEED Role

"Co-activator of prophage gene expression IbrA" in subsystem IbrA and IbrB: co-activators of prophage gene expression

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A5C8 at UniProt or InterPro

Protein Sequence (424 amino acids)

>BT2311 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MGGTRMNVYQALRERIRRIFGEYDYVYLSFSGGKDSGVLLNACVEHIRQYGGRMGVFHMD
YEVQYSLTTEYVDEMLSSNRDILDVYRCCVPFKVGSAASMYQRFWRPWDPCVRWVREMPV
EYLGTEAFDFYTPQMWDYEFQECFSFWLRKQLGVQKVACLVGIRTQESFNRWRTIYRSTP
GPSADWICPVDEGIDNVYPLYDWHTTDIWTANGRFRWKYNRLYDLYYQAGVPLNSQRVAS
PFISQAIPSLHLYRVIEPEMWGKMLGRVNGVNFAGGYGNSVAMGWRGVRLPEGMTWKKYL
FFLLDTLPEDARNNYLDKLEVSVRFWREKGGCLAKETIMKLKRLNIPFELGGTSGYRMHK
LPVRMEYLDDIDLPEFRELPSYKRMCICILKNDHCCKYMGFSPNKQEQERRRKMMDEYRS
YFNE