Protein Info for BT2268 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1026 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 19 to 1026 (1008 residues), 884.5 bits, see alignment E=1.2e-269 PF13620: CarboxypepD_reg" amino acids 21 to 81 (61 residues), 47.4 bits, see alignment 3.2e-16 PF13715: CarbopepD_reg_2" amino acids 21 to 102 (82 residues), 74.9 bits, see alignment E=6.1e-25 PF07715: Plug" amino acids 110 to 229 (120 residues), 66.4 bits, see alignment E=4.5e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 205 to 235 (31 residues), 66.2 bits, see alignment (E = 1.6e-22)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2268)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A5H1 at UniProt or InterPro

Protein Sequence (1026 amino acids)

>BT2268 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MLLLACLFVGISLVTAQTQKVTGVVISEEDGQPVVGASVLVKGTTQGTITDIDGNFNLAN
VPSSAKTLQISYIGMQTQEVAIKPMVKVTLKSDAQNLDEVIVVAYGTAKKSSFTGSAAVI
KADKIVSGSKESFDKALSGKMAGVRTASATGDPGSMAEINIRGVGSISASKSPLYVIDGV
VTKADDDMNYYGKTQSVLSTLNPEDIESMTVLKDAAAASLYGSRAANGVIIITTKKGKEG
KTNVSYSGEVGWNKMAVNAFNMMGSADLIDYTRESLANCLVTYGITDSKQAALNNIDNGG
DMFIPLLDSPATVADFIHDPSGKVNTNWKKEIYRTAFTQDHQISINGGSSKTQFYAGVGY
NKSEGIVLGSDFERISGRLNVNHKVNNWLNVALKQMIAATSQDGFRDQGDQAQGMGTSSP
IGILFAMDPTAPVKNEDGSYNKNAAWGKVTNPHLMLGGKDSDTALEWIQTKMFRSMTNAD
VTIKFCDKLSLNSIFGYDYVDNKHFEYWDRNSVNGGSVSGMGSRYTFESRVATSSSTLNY
TDTFKDMHNLNLMAGFEVENRDLLQIVTVAKRYSSHYPELANGQPDQAASSTLGAGMMSY
FASGNYNYDNKYYLSASFRRDGSSRLSEDNRWASFWSVSGAWRMSKEGFMQDMPLFTDFK
IKASYGTNGNLPSDYYGYMDLYTGSGYGSAPAIYWSRMANDKLSWEKSKNFNMGIEWNMY
DRVNLSLEYYNKKTTDLLFEVPTSLITGFDSRWENLGALKNDGFELELNSKNISNKNFTW
TSNFNLTYQRALVDKLPEGKDIQYGDGEMYLHREGESMYTFYLPEWKGVNPETGLGEFWL
DPEDHSKGVVNDYSEAGKGIVGKALPDVIGGFSNTFTYKDFDLSFLITYQFGGDMFDYPG
YFSHHDGVRIGSMNLSEDVAGNYWKNPGDKVDNPMPIYANPYRWDRFSSRTIKSTDNIRL
REMTVGYTLPVLKKHISNFRIYFRANNLAMLWSKTKNIDPDVAINGYRQADTPALRSCVF
GINIKL