Protein Info for BT2104 in Bacteroides thetaiotaomicron VPI-5482

Annotation: ROK family member transcriptional repressor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 897 PF00480: ROK" amino acids 4 to 268 (265 residues), 92.5 bits, see alignment E=1.7e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2104)

Predicted SEED Role

"mannose-6-phosphate isomerase, class I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A5Y2 at UniProt or InterPro

Protein Sequence (897 amino acids)

>BT2104 ROK family member transcriptional repressor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKYYLGIDIGGTHIKGGIVNLLTNDIHQNILSHEELNATDSTSSIITKVRKVITDIQACM
PLSKLGGIGIAMPGPCDYAKGIVAIYGVPKFQSLFGLNLKEEIKKVSDLNTVFINDASAY
ALGEYYAGAAKDTSRSIIVTIGTGLGSTFLENDTVLNELTEGIPEHGYLYNIPYRDGMAD
DFFSTRWFVNTWNMLFPDKKVTGVKEIALRASNGDNNAQSLFENFASNFVEFITPFLLNF
KPEKLIIGGNIAKASDFFLDNIQFQLKKLNLITKIDICKLWDMSPLIGSAIYTSNILENM
ENTKEKRHTQQFIAPTNSTATPSGEYDIYPAFPLGKGKIGKGINQLADWIEKHSQIKIDG
YIGVFWDELIIKLGEELRKRGKNVRFFHSSVAMKDPQTIEKMIAPYLGGDNPLFGTITDK
HLVNWFDENKLNSIQPDPEADLNIFIGTGAALSQWKAPLIYIDIPKNEIQFRMRAGAINN
LGLDYRKDNQQAYKQLYFVDWIVLNKHKKQCLPLIDLLIDGQREWDELLMISGNDLREGL
HKMSRNFFRVRPWFEPGAWGGQWMKNHIQGLNKEVNNLAWSFELMVLENGLMLESDGYRL
EVSFDFLMYSDYQNILGECSETFKYDFPIRFDFLDTFDGDNLSIQCHPRPRYIQEHFNMP
FTQDETYYILDCKNSPCVYLGFQDNIVPEEFQYTLERSQQKATKVEIERFVQKHQAKKHD
FFLIPNGTIHASGKDCVVLEISSAPYIFTFKMYDWIRMGLDGKPRPLNIQHGMNNLYFER
KGEKVIQELICHPYIMKENQECTIEHLPTHKEHFYDVYRYTFKDRIQMNTENTCHVCMIV
EGDSVCIETEDGMKQRFNYAETFVIPAAARSYTIINENPDKRIMLVKAFVKKEVTLK