Protein Info for BT1838 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative alanyl dipeptidyl peptidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 840 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF00326: Peptidase_S9" amino acids 621 to 826 (206 residues), 160.2 bits, see alignment E=1.1e-50

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1838)

Predicted SEED Role

"ApeH acylamino-acid-releasing enzyme (EC 3.4.19.1)" (EC 3.4.19.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.19.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A6N9 at UniProt or InterPro

Protein Sequence (840 amino acids)

>BT1838 putative alanyl dipeptidyl peptidase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MALAIFLATGVTMQAQDRLTQYKVRNAISVRTPIMNDSINPKGEKHTKKMLLQTPVVLHL
PDAPMQSLTADTAGYLSFEKADKDNKLYLVKTQIRAERFLKGKLKITSPVRWEVFIDGAS
KQVKDAAEDSITSGSSRDIALSLEPERDYEIIIKLLSASDDKAAPTLKCELIKDEKFKDI
ACNLDPEAKKRFSLDNTVYGNRAIAVSISPSGKYLLTRYWDNHAAKRSRTYCELTELKSG
KVLLTNLRDGMSWMPKSDKLYYTVTALTGNDVITLDPATLREETILQSIPEQSFRWSPNE
DFLIYYPREEGVKEDGPLRRIVSPADRIPNSRGRSFLAKYNLADGISERLTYGNHSTYLQ
DISPDGKYMLYSTSKENITQRPFSLSSLYQVDLETLKVDTLFYEDRFVGGAGYSPDGKQL
LLTGSPEAFGGIGKNCGNHPIANDFDTQAFIMDLSTRKIQPITKDFNPTVSPLQWNHGDG
CIYFNTDDGDCKNIYRYSPKDGKFEKLNLETDVTSAFALSEYNPGIAAYIGQSDYNAGVA
YLYDMKKKTSSLLADPMKPILEKIELGKTEPWNFTASDGTVITGKMCLPPNFDPNKKYPM
IVYYYGGTTPTTRGISNPYCAQLFASRDYVVYVIQPSGTIGFGQEFSARHVNAWGKRTAD
DIIEGTKQFCKEHPFVDEKKIGCLGASYGGFMTQYLQTQTDIFAAAVSHAGISDVTSYWG
EGYWGYSYNAIAAADSYPWKDPDLFTKQGSLFNADKINTPLLLLHGTVDTNVPIGESIQL
FNALKILGKTVEFVTVDGENHFISDYDKRIKWHNSIMAWFARWLQDQPEWWKEMYPERHL