Protein Info for BT1578 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative metal dependent hydrolase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 PF13483: Lactamase_B_3" amino acids 3 to 139 (137 residues), 32.5 bits, see alignment E=4.2e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1578)

Predicted SEED Role

"Metal dependent hydrolase (EC 3.-.-.-)" (EC 3.-.-.-)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A7E6 at UniProt or InterPro

Protein Sequence (243 amino acids)

>BT1578 putative metal dependent hydrolase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MTLDYIYHSGFAIEAEGVTVIIDYYKDSSETEHNRGIVHDYLLQRPGKLYVLATHFHPDH
FNREILTWKEARPDIRYIFSKDILKSHRAKPEDATYIKKGETYEDETIRIEAFGSTDVGS
SFLIHLQDWNIFHAGDLNNWHWSEESTEAEIRKANGDFLAEVKYLKEKAPKIDLALFPVD
RRMGKDYMKGAKQFIEQIKTTIFVPMHFSEDYEGGNALRDFAENAGCRFVSITHRGESFE
ITK