Protein Info for BT1460 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 825 transmembrane" amino acids 42 to 63 (22 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 75 to 153 (79 residues), 53.7 bits, see alignment E=2.3e-18 PF13715: CarbopepD_reg_2" amino acids 76 to 165 (90 residues), 54.7 bits, see alignment E=8.7e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1460)

Predicted SEED Role

"TonB-dependent receptor plug domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A7R4 at UniProt or InterPro

Protein Sequence (825 amino acids)

>BT1460 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKMNKTMLLGEVANRSGIPADECGVVLKTFERVLCEELTRKLYRYGGWILLLIGLFVSAF
AFGQTSERKGRPVQTIRGMVVDGDSKYPIPYATIRLSDKEGMGTTTDSLGRFTIPQVPVG
RHTVEAAFMGYEPGIFREILVTSAKEVYLEIPLKESVNELSEVVVRARTNKEEAMNKMAT
TGARMLSVEEASRYAGGFDDPARLVSAFAGVAPSVSSNGISIHGNAPHLLQWRLEDVEIP
NPNHFADIATLGGGILSSLSSQVLGNSDFFTGAFPAEYGNAVSGVFDMKLRNGNNQKNEN
TIQVGIMGIDVASEGPLSKKHKASYIFNYRYSTTGLLNLDGGTMDYQDLNFKLNFPTKMA
GTFSVWGTSLIDKFKSDMERNPEKWEYLGDRSESRDKQYMAAGGISHRYFFNSDASLKTT
VAATYSQLDGGASMFNHALESTPYMDLESRHTNLILTSTFNRKFSNRFTNKTGFTYTAMF
YDMNLAIAPYEAQLLETVSKGDGNTSLISAYNSSSVGLSDRWTLNAGIYGQYLTLNNKWS
VEPRAGLKWQATPKATFALAYGIYSRMEKMDVYFVKTKSTGNQSVNKNLDFTKAQHIMLS
FGYKISDRMNLKIEPYVQFLHDVPVMADSSYSVLNRSDFYVEDALVNKGRGRNIGIDITL
ERFLEKGLYYMISGSLFDSRYRGGDGVWYNTKFNRNYVINGLIGKEWMLGRNKQNILSIN
LKLTLQGGDRYSPIDMEATMKHPDKEVQYDERKAFSKQYSPMFIGNYTVSYRINKKKVSH
EFAVKGLNFMGTKEHYGHEYNVKTGKIDATDGSTVLTNVSYKLEF