Protein Info for BT1397 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative membrane protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 100 to 118 (19 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 162 to 180 (19 residues), see Phobius details amino acids 192 to 214 (23 residues), see Phobius details amino acids 229 to 251 (23 residues), see Phobius details amino acids 260 to 279 (20 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details PF00892: EamA" amino acids 15 to 146 (132 residues), 46.2 bits, see alignment E=2.6e-16 amino acids 161 to 302 (142 residues), 76.2 bits, see alignment E=1.4e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1397)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A7X7 at UniProt or InterPro

Protein Sequence (315 amino acids)

>BT1397 putative membrane protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKSQNPSKRNLPGVIIAYFLIYVVWGSTYFFIGVALKDFSPFLLGALRFTTAGLILLGIC
YLRGEQIFKKSLVKRSAVSGIVLLFVDMAVVMLAQRYLTSSLVAIIASSTALWILLLDVP
MWRTNFRNPLTIAGGGIGFGGVVMLYAEQLNAEWLHPQSERGILLLVFGCISWALGTLYA
KYRSSREEEVNAFAGSAWQMLFASVMFWICAVVNGDVREADLSTVSVTSWFSLLYLISFG
SLLAYSAYVWLLKVRPAAEVGTHAYVNPFIAVLLGVSFGNEQVTFVQLSGLLVILLGVML
ISRKRNKMKSTAISR