Protein Info for BT1210 in Bacteroides thetaiotaomicron VPI-5482

Annotation: cytochrome D ubiquinol oxidase subunit I (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 transmembrane" amino acids 22 to 45 (24 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 98 to 123 (26 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 400 to 424 (25 residues), see Phobius details amino acids 436 to 455 (20 residues), see Phobius details amino acids 485 to 506 (22 residues), see Phobius details PF01654: Cyt_bd_oxida_I" amino acids 12 to 513 (502 residues), 557.4 bits, see alignment E=8.7e-172

Best Hits

KEGG orthology group: K00425, cytochrome bd-I oxidase subunit I [EC: 1.10.3.-] (inferred from 100% identity to bth:BT_1210)

Predicted SEED Role

"Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases (EC 1.10.3.-)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A8F7 at UniProt or InterPro

Protein Sequence (520 amino acids)

>BT1210 cytochrome D ubiquinol oxidase subunit I (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MIESIDTSLIDWSRAQFAMTAMYHWIFVPLTLGLAVVMGIMETLYYKTGNEFWKRTAKFW
MKLFGINFAIGVATGLILEFEFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMF
FGWDKVSKRFHLASTWLTGLGATISAWWILVANAWMQHPVGMEFNPDTVRNEMVDFWAVA
TSPVAVNKFFHTVLSGWVLGGVFVVGISCWFLLKKRNREFALASIKIGAIFGLVSSLLAV
WTGDGSGYQIAQTQPMKLAAVEGLYEGGTNVGLVGIGMLNPEKKTYNDGKDPFLFRIEIP
SMLSFLAERDVDGYVPGITNIIEGGYQLKDGTTALSAAEKIERGKTAIGALAAYRAAKSA
GHEEDAAVAYQVLQENMPYFGYGYIKDVNQLVPNVPLNFYAFRIMVILGGYFILFFIVVL
FFIYKKDLSKMRWMHWIALLTIPLAYIAGQAGWVVAECGRQPWAIRDMLPTSAAISKLDV
GSVQATFFIFLILFTVMLIAEIGIMVKAIKKGPEEEISNR