Protein Info for BT1042 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1097 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF07660: STN" amino acids 54 to 105 (52 residues), 44.4 bits, see alignment 2.8e-15 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 118 to 1097 (980 residues), 718 bits, see alignment E=2.5e-219 PF13620: CarboxypepD_reg" amino acids 119 to 185 (67 residues), 38.9 bits, see alignment 2.4e-13 PF13715: CarbopepD_reg_2" amino acids 119 to 198 (80 residues), 68.6 bits, see alignment 9.4e-23 PF07715: Plug" amino acids 208 to 333 (126 residues), 62.4 bits, see alignment E=1.3e-20 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 309 to 339 (31 residues), 54.6 bits, see alignment (E = 7e-19) PF00593: TonB_dep_Rec" amino acids 498 to 936 (439 residues), 84.3 bits, see alignment E=4.4e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1042)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A8X5 at UniProt or InterPro

Protein Sequence (1097 amino acids)

>BT1042 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKEIIKHKFPYLLFFLLLFSSFASAYGQERMITLNLSKVPLNTALKEIEKQTSMSVVYNT
NDVDINRVISIKVSKESLTNVMGQLFKGTNISYSIVDKHIVLSTKKEVEQQKKTPIVATG
TVTDAQGEPLIGVSILVKGTATGAITDMDGNFKIQAAKGDVLEISYIGYASQSITLANAQ
PLKVTMGEDTQTLDEVVVTALGIKREQKALSYNVQKVNNDALTSVKDANFVNSLNGKVAG
VNIQRSASGVGGSTRVTMRGNKSISGDNNVLYVVDGVPIGNQADRTGDGTGFGSGRTSGE
GIANFNPDDIESVSVLTGPSAAALYGASAANGVILINTKKGEAGKMRIDVSSSVEFMTPL
TMPKFQNRYGISGNYYSWGDKLENQSSYDPKDFFELGATFNNSFNLSTGNDKNQTYFSIA
AVNSDGIVPNNKYHRYNVTLRNTAKFLNDKLTLDASASYIREYYNNMISYGTYFNPIVGA
YLYPRGEDFEKEKYFERYNSELGYSQQQWSPGDFGMDIQNPYWIAYRNIRPEVKDRYMLY
ASLKYDITNYLNVAGRVRLDNTYTEKEDKRYASTINTYASTNGRYTYSNETFRQKYADIM
VNFDKQFAEIYHATINAGTSFEEYDTKGRGYGGQLLLVPNKFVYSNIDPTQSTASQTGGD
SRRRNFAVFASAELSWNSALYLTLTGRADKPSQLVNSDDPWIFYPSVGLSAIVTELLPNN
IKEKLEPTLGFLKVRASYTEVGSPIPYTGLTPGTLTHELEGGTFKPFKYYPISNLKAERT
RSYEVGLDSKWFNNTITFGVTYYHSNTYNQLLKATLGSNFEYMFVQAGNVQNRGLELSLG
FDKKFGDFNYNTTFTATTNKNKIIQLARDVLNPVTNTLIDLTDIQVGRFRLREGGEIGTV
YANEWLKRDGDNYIDYQPGQALTTETTSPYKLGSVNPKWNLGWQHGFSYKGFNLNLLFTA
RIGGIAISKTQAMLDRYGVSEASADARDAGGVSLGYFKVDPKTYYDAVSNLDAYYTYSAT
NVRLQEARLTYTFPNKWFKGTVNNLSLSVYGTNLWMIYNKAPYDPELTASTGTFGQGYDY
FMLPSQSTYGLSLKFGF