Protein Info for BT1019 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative secreted hydrolase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 923 PF08531: Bac_rhamnosid_N" amino acids 170 to 340 (171 residues), 222.6 bits, see alignment E=5.9e-70 PF05592: Bac_rhamnosid" amino acids 365 to 459 (95 residues), 99 bits, see alignment E=2.6e-32 PF17389: Bac_rhamnosid6H" amino acids 477 to 825 (349 residues), 366.4 bits, see alignment E=3.2e-113 PF17390: Bac_rhamnosid_C" amino acids 847 to 916 (70 residues), 81.2 bits, see alignment 7.6e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1019)

Predicted SEED Role

"alpha-L-rhamnosidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A8Z8 at UniProt or InterPro

Protein Sequence (923 amino acids)

>BT1019 putative secreted hydrolase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MQEGLVVVESCPRLGWAMESPENGTRQTAYEIEIREAFTGRSVWNSGKVTSSQSQLVPTE
GADICLNNPFNYSWRVRVWDETDTPSEWSQEAKFRLASDDLSSGKWIGAITRKDSHLPEG
RKFHGGELKKPEVKAAWEAVDTLAKKSICLRRTFQTGEAKGKNANRKSGKKIVEATAYVC
GLGFYEFSLNGKKIGDSEFAPLWSDYDKSVYYNTYDVTEQLQDGENVVGILLGNGFYNVQ
GGRYRKLQISFGPPTLLFELVINYEDGTRETIRSDHEWKYDLSPITFNCIYGGEDYDARR
EQKGWNQVGFNDSHWRPVVVQEAPKGVLRSQMAPPVKIMERYDIQKVTKLNSEQVMAASK
STKRTVDPSAVVLDMGQNLAGFPEITVRGKRGQKVTLIVAEALMDEGACNQRQTGRQHYY
EYTLKGEGDEIWHPRFSYYGFRYIQVEGAVLKGQKNPQKLPVLKNIQSCFIYNSAKKVST
FESSNRIFNAAHRLIEKAVRSNMQSVFTDCPHREKLGWLEQVHLNGPGLLYNYDLTAYAP
QIMQNMADAQHPNGAMPTTAPEYVVFEGPGMDAFAESPEWGGSLVIFPFMYYETYGDDSL
IKKYYQHMRRYTDYLKTRADNGILSFGLGDWYDYGDFRAGFSRNTPVPLVATAHYYMTVM
YLIKAARMVGNEFDVRYYSSLAYDIMVAFNKRFLDSNTAQYGTGSQASNALPIFLQMIQS
TGDKGDYTPDASLAAKVLTNLIKDVESHGNRLTTGDVGNRYLIQTLARNGQHELIYKMFN
HEEAPGYGFQLKFGATTLTEQWDPRQGSSWNHFMMGQIDEWFFNSLIGIRPSTTLSASVN
EKDEPMQGYQKFVIAPKPVGDLKYVKSTYETLYGTILVDWTRQSGTFTLNVSVPVNTTAI
VYLPGEKEPKEVQSGTYKFVAAE