Protein Info for BT0986 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein, putative DNA-binding protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1105 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF17132: Glyco_hydro_106" amino acids 36 to 709 (674 residues), 472.4 bits, see alignment E=1.6e-145 amino acids 836 to 893 (58 residues), 45.8 bits, see alignment 1.7e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0986)

Predicted SEED Role

"glycoside hydrolase family 2, sugar binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A931 at UniProt or InterPro

Protein Sequence (1105 amino acids)

>BT0986 conserved hypothetical protein, putative DNA-binding protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKSRLKQQIFAISLLACTAISPANALQTHLLREQFQNPSDEAKPWTFWYWMFGAVSKEGI
TADLEAMKRAGLGGTYLMPIKGIKEGPQYNGKAQQLTPEWWEMVRFSMEEADRLGLKLGM
HICDGFALAGGPWMTPKESMQKIVWSDTIVDGGKIKGLHLPQPEAYEGFYEDISLFALPV
KEEAADVMPAQITCANIATGNHIDIKKTVNMDDAGVIRSSYPCYIQYEYEQPFTCRNIEI
ILSGNNYQAHRLKVMASDDGVNYRLVKQLVPARQGWQNTDENSTHAIPATTARYFRFYWT
PEGSEPGSEDMDAAKWKPNLKIKELRLHREARLDQWEGKAGLVWRVASSTKKEEIGEQDC
YALSQIINLTDPFKNSPSDNFKERTLTATLPKGKWKLLRMGHTATGHTNATAGGGKGLEC
DKFNPKAVRKQFDNWFAQAFVKTNPDVARRVLKYMHVDSWECGSQNWSDTFAAEFRKRRG
YDLMPYLPLLAGIPMESAERSEKILRDVRTTIGELVVDVFYQVLADCAKEYDCQFSAECV
APTMVSDGLLHYQKVDLPMGEFWLNSPTHDKPNDMLDAISGAHIYGKNIIQAEGFTEVRG
TWNEHPGILKALLDRNYALGINRLFFHVYVHNPWLDRKPGMTLDGIGLFFQRDQTWWNKG
AKAFCEYITRCQSLLQYGHPVADIAVFTGEEMPRRSILPERLVPSLPGIFGAERVESERI
RLANEGQPLRVRPVGVTHSANMSDPEKWVNPLRGYAYDSFNKDALLRLAKAENGRMTLPG
GASYKVLVLPLPRPMNPDPAALSPEVKQKINELKEAGILIPSLPYKEDDFSSYGLERDLI
VPENIAWTHRQGEQGDIYFIANQLEETRTFTASMRIDGRKPECWNPVTGEINADIPYEQK
SHRTEITLTLAPNESVFIVYPAEEDDKETSEKERKEKKDSVKEASETGLEATEYTVTFTA
NGKTIQRQELFDWSKEEDEQIRYYSGTAVYKTTFRWKSKVKEDQQVYLNLGKVCDLATVR
VNGIDCGTIWTAPYRADITAALKKGVNELEIEVTNTWANALKGADEGKAPFDGIWTNAKY
RRAENTLLPAGLLGPLNFDVANKNK