Protein Info for BT0630 in Bacteroides thetaiotaomicron VPI-5482

Annotation: exodeoxyribonuclease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 TIGR00195: exodeoxyribonuclease III" amino acids 1 to 252 (252 residues), 291.9 bits, see alignment E=4.6e-91 TIGR00633: exodeoxyribonuclease III (xth)" amino acids 1 to 252 (252 residues), 308.9 bits, see alignment E=2.8e-96 PF03372: Exo_endo_phos" amino acids 4 to 228 (225 residues), 116.7 bits, see alignment E=6.6e-38

Best Hits

KEGG orthology group: K01142, exodeoxyribonuclease III [EC: 3.1.11.2] (inferred from 100% identity to bth:BT_0630)

Predicted SEED Role

"Exodeoxyribonuclease III (EC 3.1.11.2)" in subsystem DNA repair, bacterial (EC 3.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AA35 at UniProt or InterPro

Protein Sequence (253 amino acids)

>BT0630 exodeoxyribonuclease (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKIITYNVNGLRAAASKGLPEWLVQENPDILCLQETKLQPDQYPAEVFEALGYKAYLYSA
QKKGYSGVAILTKQEPDHVEYGMGIEAYDNEGRFIRADFGDLSVVSVYHPSGTSGDERQA
FKMVWLEDFQKYVTELRKTRPNLILCGDYNICHEPIDIHDPVRNATNSGFLPEEREWMTR
FLSAGFIDSFRLLYPEKQEYTWWSYRFNSRAKNKGWRIDYCMTSEPVRPMLKSASILNDA
VHSDHCPMALEIE