Protein Info for BT0494 in Bacteroides thetaiotaomicron VPI-5482

Annotation: protoporphyrin IX magnesium chelatase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 transmembrane" amino acids 825 to 845 (21 residues), see Phobius details PF02514: CobN-Mg_chel" amino acids 2 to 743 (742 residues), 560.9 bits, see alignment E=3.1e-172

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0494)

Predicted SEED Role

"CobN/magnesium chelatase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAH1 at UniProt or InterPro

Protein Sequence (854 amino acids)

>BT0494 protoporphyrin IX magnesium chelatase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MEKIKIYNNSQKANKDQESLAVKTLTVKMGIHRDLGLDSMANKPYTEDEIARVENFAEEL
ATEKITGQLYTMGVPYEPERITSSVYAMATEPIAYSLFALDKQRGKATESAEKHRSVFTQ
QYLMPARLLVERLMANPSLATDELICHTAGITPQELAKARQIEAERNAPKGMMAMMMAAA
AKKDQADNEPSGNGHPASAKMEKGPHGKMPAGMKEAMKKMGANMDPEKAMEMAKSMGASP
EALKKMEASMKANKDTSTDASGKPAMAGKTEKPQGMSAMMAAMGKAPKEYSKEEVEFALA
VAEVERTIKNVGNYKNALLTSPEEELSSLMNALKGGYTAPTPGGDPIANPNTLPTGRNMY
AINAEATPTESAWEKGIALAKQTIDRYKQRHNDSIPRKVSYTLWSSEFIETGGATIAQVL
YMLGVEPVRDAFGRVSDLKLIPSTELGRPRIDVVVQTSGQLRDLAASRLFLINRAVEMAA
AAKDDKYENQVASSVIEAERVLTEKGLSPKDAREISTFRVFGGANGMYGTGIQEMVESGD
RWENESEIADTYLNNMGAYYGSEKNWEVFQKFAFEAALTRTDVVVQPRQSNTWGALSLDH
VYEFMGGMNLAVRNVTGKDPDAYLSDYRNRNHMKMQELKEAVGVESRTTILNPTYIKEKM
KGGASSASEFAEVITNTYGWNVMKPAAIDKELWDNIYNVYVKDELNLGVKQYFEQQNPAA
LEEMTAVMLESARKGLWQASEEQVAELSKLHTEIVNTYRPSCSGFVCDNAKLRDFIASKA
DAQTATQYKENISKIREAKASGSNKGVVMKKEEMNQTAENQTNTLSNVAVGIAVIIVILA
LILFVRKRRKSSQM