Protein Info for BT0483 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 914 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 32 to 914 (883 residues), 580.9 bits, see alignment E=6.4e-178 PF07715: Plug" amino acids 45 to 153 (109 residues), 58.8 bits, see alignment E=7.2e-20 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 129 to 159 (31 residues), 57.3 bits, see alignment (E = 1e-19) PF00593: TonB_dep_Rec" amino acids 300 to 870 (571 residues), 85.2 bits, see alignment E=9e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0483)

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAI1 at UniProt or InterPro

Protein Sequence (914 amino acids)

>BT0483 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKQHYRLTIWSLFFLITSSGSAFAQRKTITPIDSLITVGYATGSLKTISGSVEKITETQM
NKDQITNPLEAIRGRVPGLTIQRGTNGPAALDAVRLRGTTSLTSGNDPLIIVDGVFGDLS
MLTSIYPTDIESFTILKDASETAQYGSRGASGVIEITTKKGMSGKTQVSYNGIFGISTVY
KNLKMLSADDFRRVASERGISILDKGNNTDFQKEIEQTGLQQNHHIAFYGGSNESSYRVS
LGFMDRQGVILNEDMKNFTSNMNMTQRMFDGFLNCELGMFGSIQKNHNLVDLQKTFYSAA
TFNPTYPNHKDPDSGSWDGITTASQITNPLAWMEVQDHDATSHISTHARLTFNLMDELKL
VLFGAYTYNIIENSQYLPTSVWAHGQAYKGTKKMESLLGNMMLTYKKGWKKHYFDALALA
ELQKETYTGFYTTVTNFNTDKFGYHNLQAGALRPWEGTNSYYEQPHLASFMGRFNYTYAD
RYSLTMTARTDASSKFGANHKWGFFPSVSAAWVISEEKFMKRLPVIDNLKFRIGYGLAGN
QSGIDSYTTLSLVKPNGVIPVGNSAAVSLGDLRNTNPDLKWEVKHTFNTGIDLAMFGNRL
LLSANYYNSKTTDMLYLYNVSVPPFTYNTLLANIGSMRNSGLEIAIGITPLKTQDMELNI
NANITFQQNKLLSLSGMYNGELISAPEYKSLASLDGAGFHGGYNHIVYQVVGQPLGVFYL
PRANGLVSDGNGGYTYDIADLNGGGVSLEDGEDRYVAGQAVPKTILGSNLSFRYKRFDIS
VQINGAFGHKIYNGTSLTYMNMNIFPDYNVMQEAPARNIKDQTATDYWLENGAYVNFDYV
TLGWNVPIEKVQKLKKYVRSLRLAFTVNNLATISGYSGLSPMINSSTVNSTLGLDDKRGY
PLARTYTLGLSINF