Protein Info for BT0439 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1039 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 52 to 1039 (988 residues), 1033 bits, see alignment E=0 PF13620: CarboxypepD_reg" amino acids 54 to 122 (69 residues), 40.1 bits, see alignment 6e-14 PF13715: CarbopepD_reg_2" amino acids 54 to 134 (81 residues), 57.2 bits, see alignment 2.2e-19 PF07715: Plug" amino acids 143 to 246 (104 residues), 49.2 bits, see alignment E=1e-16 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 222 to 252 (31 residues), 58.9 bits, see alignment (E = 3.1e-20)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0439)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAM5 at UniProt or InterPro

Protein Sequence (1039 amino acids)

>BT0439 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MMSDLRKNIFSIKIWTVTTFCLLSLVNMNASNTLAHSLQKDEIKEVKDNPGKKVTGKVLD
EFGEPIPSASILVEGRSRGVITDLDGTFVIEVLPTDKLVVSFLGMETQTILVGKQTNIVV
KMQPQTAELDEVTVVAYGKQRKASVIGAINTVSMNELKMPVAKLSSGLAGQLAGIVVMQR
SGEPGAGADFWIRGINTFGAGNKPLVLVDGVERSMDLVDVEDIASFSILKDATATALYGV
RGANGIVLITTKRGTESAPKINARVEYGFTNPVRMPELANTEQWINYYNDITLESSGRLA
IQPEEKAKYLNNTDPDLYPNVDWMQTLFKDFSNTTRVNINVTGGSPKIRYYVGGSFYSEG
SVFNISDKDRYDASMRYNKFSFRSNIDINVTSSTELSLSLSNQYETKNRPYGSLSDLYAY
MIRTSPIATPTIYSDGTLAKPSTGTNPYNSLNNSGYSQDFFNNAQSLISLTQDFSKMVTP
GLKANVKFSWDAYNAHTLNRIVTPSTYYATGRDEEGNLDFVRSTEGSDYMKLTRTNSGTR
TINFEASANYDRLFGEKHRVGALFLFSMRNYTDNFPGNYVDAFAHKNIGIAGRATYSYYD
RYFAEFNFGYNGSENFAPDKRFGFFPSFAIGYMLSNEAFWDPLRSTIHLLKIKGSYGEIG
NDQIGGNRRFAFNSTMKEGQYGYIFGTNPGSGSIVGISTGIPGNLNVSWEKAQKANVGLE
LGLFDQLKFQLDYFYEKRTGIYIQQESVPSIVGLNETQYVNLGEMKNQGFDGSMEYEQRF
NDWYVSARANFTYNRNKKLYDDKPTPIWPYQSEAGFAYRQQRGLIALGLFESEEDIANSP
KQNFGNVRPGDIKYKDINGDNVIDAYDKVAIGYTDVPEINYGFGISLGWKGFDASLFMQG
VGNVTRIIGGDALYGASDNIERLGQIYADVAEKRWTTSNPNPNATYPRLSMSKVENNLQP
STYWQRNMSFLRLKNVEIGYTLPKHIYKRLGMSSIRVYAQGVNLLTFSKFKLWDPELDSN
YGNIYPQMRTITLGLNLNF