Protein Info for BT0341 in Bacteroides thetaiotaomicron VPI-5482

Annotation: Na+/glucose cotransporter (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 50 to 72 (23 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 123 to 148 (26 residues), see Phobius details amino acids 156 to 176 (21 residues), see Phobius details amino acids 187 to 210 (24 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 317 to 343 (27 residues), see Phobius details amino acids 363 to 385 (23 residues), see Phobius details amino acids 397 to 417 (21 residues), see Phobius details amino acids 425 to 447 (23 residues), see Phobius details amino acids 459 to 480 (22 residues), see Phobius details amino acids 501 to 520 (20 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 38 to 433 (396 residues), 272.2 bits, see alignment E=4.3e-85 PF00474: SSF" amino acids 39 to 433 (395 residues), 189.2 bits, see alignment E=5.9e-60

Best Hits

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 100% identity to bth:BT_0341)

Predicted SEED Role

"SSS sodium solute transporter superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAX1 at UniProt or InterPro

Protein Sequence (523 amino acids)

>BT0341 Na+/glucose cotransporter (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MHAKFLDTLDWGILIAYFLILIAIGIWASSKRKKGSSLFLAEHSLRWHHIGFSMWGTNVG
PSMLIASASAGFTTGIVSGNYAWYAFVFICLLAFVFAPRYLGSRVSTLPEFMGKRFGQST
RNILAWYTIVTILISWLALTLFAGGVLIRQVFDIPMWQSALILLIISAFFTMLGGLKAVA
YTNVYQMILLILVSAALAIVGIYKVGGISALTDAVPADFWNLFRPNDDTAFPWLPIILGY
PVMGVWFWCTDQSMVQPVLAAKSLKEGQLGTNFTGWLKILDVPLYILPGIICLALFPQLE
NPDEAYMTMVTHLFPVGMVGLVLAVLTAALVSTIGSALNALSTVFTMDIYVKKIRPQAKQ
KEIIRVGQVVTVAGALISVIITIAIDSIHGLNLFNVFQSVLGFIAPPMAAVFLFGVFWKR
TTTLAANAALTVGTVFSIGVGVLYLWVFPADQYSAWPHFMLLSFYLFVIIGIGMVVVGLL
DKTPQTAILNMEKIEEKPARIVLILWGLLIVTMIGLYIFFNGH