Protein Info for BT0317 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1062 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 41 to 1062 (1022 residues), 764.5 bits, see alignment E=2.3e-233 PF13620: CarboxypepD_reg" amino acids 43 to 102 (60 residues), 40.8 bits, see alignment 3.4e-14 PF13715: CarbopepD_reg_2" amino acids 43 to 122 (80 residues), 70.3 bits, see alignment 1.7e-23 PF07715: Plug" amino acids 131 to 254 (124 residues), 67.5 bits, see alignment E=2.1e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 230 to 260 (31 residues), 52.1 bits, see alignment (E = 4.2e-18)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0317)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAZ5 at UniProt or InterPro

Protein Sequence (1062 amino acids)

>BT0317 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MFKPLKSVSVLLLLFAMPAAISYAASENGATSVSVTQQNGTCKGVVKDKAGEAVIGASVV
VKGTTNGVITDLDGNFVLSNVPDGATIQISYVGYTPQEVKFTGKPLDITLQEDTQTLDEV
VVTALGIKRQKRSLGYSTTTVGGKDFTEARTTNIGNALSGKIAGVSVSGNATGPGGSSRV
VIRGNASLTGNNQPLYVIDGVPFDNTNIGSAGQWGGKDMGDGLSSINPDDIADIQVLKGA
AASALYGYRGGNGAILITTKSGQKGKPVSVEFNNNLAFDVIYDYRDFQNVYGQGTQGNRP
LSADVAKATETSSWGEVMDGKKAVNFLGNEYAYSPVDNWKNFYRTGINNTTTLAVSGASD
KISYRFGVSNMAVKGILPNSSISQQGINMNTTYDISSKVHLMVNANYVFDKNKGRSNLSD
GNSNTNAALLYHANSFDIRWMERENPDCDWGTGADGKELLGGTNGYFNNPYWLQYRVTNE
TNRNRLTGGMTLKYDIFDWLYIQGAVTRDGYNLEYSEVKPIGSASPEDPRGYIKEYTQNF
SEMNLNYLIGFNKTFGDWSVGATFGGNRQRNITKKYGLDDKASSFFVPDFYSSSNTAKHV
YKKEYTEYRVNSIYGTADLGYKNQVFLNLTGRNDWFSTLDPDNNHYFYPSIGMSWVFSDT
FKTPDWFTFGKVRASYAAASNGTKAYQNLLTYKVDNYQSNGQPVVTINNSTVPNKGLKPV
QISEWEIGLNLSFLDNRLSLDAAYYVKTTKDDIVQVTTSGASGFESAIQNVGEIRNNGVE
VMVNAVPVHTKDFNWNSTFNIAYNSSDVKYLGIDGTGEKIKRLTLDGANSRVGSVSVQNI
LGHPYGELVGYEYKRTSDGQVIFENGLPVHSDEVQVLGNGVYKVTGGWRNEFTYKNITLS
FLIDFKAGAKMFSGTNLSLYSNGLHKNTLQGRGADGKGTMVGNGVMSDGKGGYVKNTVAV
SAQDYWQAITSQNIAEEFVYNASFIKLRELSVGYTLPQAWLNKQTLIKGVTLSLVGRNLW
TILKHTDNIDPESAYNNGNAQGLELNGYPATRNVGFNVNVKF