Protein Info for BT0204 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 169 PF03162: Y_phosphatase2" amino acids 26 to 136 (111 residues), 40.6 bits, see alignment E=6e-14 PF22741: PTP-NADK" amino acids 30 to 145 (116 residues), 35.8 bits, see alignment E=1.6e-12 PF22785: Tc-R-P" amino acids 31 to 123 (93 residues), 44.2 bits, see alignment E=7.5e-15 PF13350: Y_phosphatase3" amino acids 33 to 136 (104 residues), 36.2 bits, see alignment E=2e-12 PF22784: PTP-SAK" amino acids 35 to 137 (103 residues), 33.7 bits, see alignment E=1.1e-11 PF00102: Y_phosphatase" amino acids 84 to 130 (47 residues), 27.1 bits, see alignment E=9.7e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0204)

Predicted SEED Role

"Protein tyrosine/serine phosphatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ABA6 at UniProt or InterPro

Protein Sequence (169 amino acids)

>BT0204 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MSFSVYGQNINAEKITVPDSKLTNLYQIDSGVYRSEQPSDADFKALEKYGIREVLNLRNR
HSDDDEAAGTKIKLYRLKMKAHSVSEDQLINALRIIKNRKGPIVFHCHHGSDRTGAVCAM
YRIVFQGVSKQKAIQEMTEGGFGFHRIYKNIIRTIEKADIERIKREVLQ