Protein Info for BT0117 in Bacteroides thetaiotaomicron VPI-5482

Annotation: arsenical resistance operon trans-acting repressor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 108 PF06953: ArsD" amino acids 1 to 103 (103 residues), 140.5 bits, see alignment E=1.7e-45

Best Hits

Swiss-Prot: 42% identical to ARSD1_ECOLX: Arsenical resistance operon trans-acting repressor ArsD (arsD) from Escherichia coli

KEGG orthology group: None (inferred from 100% identity to bth:BT_0117)

MetaCyc: 42% identical to ArsD monomer (Escherichia coli)
RXN-22365

Predicted SEED Role

"Arsenical resistance operon trans-acting repressor ArsD" in subsystem Arsenic resistance

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ABJ3 at UniProt or InterPro

Protein Sequence (108 amino acids)

>BT0117 arsenical resistance operon trans-acting repressor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKTIEIFDPAMCCPTGLCGTNINPELMRIAVVIETLKRQGVVVTRHNLRDEPQVYVSNKT
VNQYLQKNGAEALPITLVDGEIAVSKDYPTTKQMSEWTGINLDLMPVK