Protein Info for BT0065 in Bacteroides thetaiotaomicron VPI-5482

Annotation: alpha-galactosidase precursor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 845 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF16499: Melibiase_2" amino acids 418 to 548 (131 residues), 76.5 bits, see alignment E=2.3e-25 PF17801: Melibiase_C" amino acids 764 to 842 (79 residues), 43.1 bits, see alignment E=3.7e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0065)

Predicted SEED Role

"alpha-galactosidase precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ABP5 at UniProt or InterPro

Protein Sequence (845 amino acids)

>BT0065 alpha-galactosidase precursor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKKISIANAITVLAASAFLIACNAYDQDLSPGGNTVIEAVCPAPALEEPATRTAVDPTAY
TSGEIGINWLPADRIGVYSATTANACFTNQSDQETDKTSFAGNLQNGETPLYAYYPYTET
AGTAPTAFKGTLPLTQHYSTATRELEGDWKVGTPQGSSASRFTFEHIFAFLKFDINAGGT
DVAGERLLSVSLTVPDKQLGGGFTCDLSTRAVTFTPATDASTVTMEWTDTPELSASTFHG
YMNVAPVTGIAGTEISIQIKTNLHIITFTETMKADAFKSNTYYTVPLTLSRFKDKWTMEE
NPDAKEENAAWVTGLQSRLACANTVFAIAGQPFMHKIRVPQSTSQQYHAVVPVKNGVKRV
YNLPEGLTWNAGRCLVEGKAPAAGDYVYSVEFTVGGATYKEGIKLHVAVRAADLQSPTPM
MGWQTWNVFKDKIGYDILASQLVGMKEKGLIDAGYRYFGVDDCWQVKSENDNGHQIPDAS
KFPTANGVNGMARMANLIHDYGLKAGIYTDCGTKTCEKYFASYGYEELHAQDYKGWGYDF
VKEDWYYDLDMAPVGATPSTFVDGYAGLGSYWNTSEMAQELYTKMGKALNDRGLMLYVCE
WGIHDPWKWGAETGATCWRMTYDHRDGWWGKIDSGLFGKKNDGDENANGVGVHNTIVLMR
HLWPYVGINRYNDADMICVGIRGSGQSSSDCVYNQAGGLTSTEAETSFAMWCMWSSPILL
GFDMTKDMSSADLAHDLALVKNEELIAINQDALGQGAEYIKSADGIDYYQKDLADGDVAI
AAVNLSDNSATYTISMADYDALDLSESYSARDLIGQKDAGTLSASSSLTGSLAAHGTFVV
RLKKQ