Protein Info for DVUA0019 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: type II DNA modification methyltransferase, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 PF02384: N6_Mtase" amino acids 11 to 246 (236 residues), 32.9 bits, see alignment E=6.7e-12 PF07669: Eco57I" amino acids 125 to 228 (104 residues), 85.8 bits, see alignment E=5.8e-28 PF12950: TaqI_C" amino acids 402 to 502 (101 residues), 27.4 bits, see alignment E=5.1e-10

Best Hits

Swiss-Prot: 65% identical to MTP7_PSEAI: Modification methylase PaeR7I (paeR7IM) from Pseudomonas aeruginosa

KEGG orthology group: None (inferred from 100% identity to dvu:DVUA0019)

Predicted SEED Role

"FIG00608060: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72WS0 at UniProt or InterPro

Protein Sequence (552 amino acids)

>DVUA0019 type II DNA modification methyltransferase, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MDALASQGDVETRGAIFTREEVVDFILDLVGYNDDQNLFMKRILEPSFGGGDFIFRIMER
LFRSWRSTKPSENVVDVLGDAIRGFEIHRDTFLATHRAVMSRIENEGFSSSTAKCLADRW
LSNDDFLLAPHCGKFEFVVGNPPYVRQELIPNLLLKEYRTRYHTMYDRADIYIPFIEHSL
SLLTRKGSLGFICSDRWMKNRYGTLLRKLIADRFNLKFYVDMVGTQAFQSSVVAYPAITV
ISREKQVATRVAQRPCISRAELRSLASELTAKRLLKESVYHVRELSHITKGGEPWLFESA
DKTALVRRLERSYPTLEEAGCKVGIGVATGADKSFIGRFDDLDVEPDRKLPLVMTQDIAS
GEVKWRGLGLVNPFNDSGTLVNLQKYPRLSRYLQERKEVLVRRHCAQKNPTKWYKTIDKI
VPSLASQEKLLIPDIKGNAHVVYEQGSLYPHHNLYYVISCTWDIRALQAVLLSGVAKLFV
EVYSTKMRGGFLRFQAQYLRRIRIPFWEDVSLGLREELIVAAKSRNLEACNAAAYRLYAL
TGEERAAIEGLG