Protein Info for DVU0601 in Desulfovibrio vulgaris Hildenborough JW710

Name: b1396
Annotation: phenylacetic acid degradation protein PaaI (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 transmembrane" amino acids 53 to 66 (14 residues), see Phobius details amino acids 71 to 72 (2 residues), see Phobius details PF14539: DUF4442" amino acids 9 to 125 (117 residues), 35.6 bits, see alignment E=1.6e-12 TIGR00369: uncharacterized domain 1" amino acids 16 to 127 (112 residues), 92.2 bits, see alignment E=1.2e-30 PF13622: 4HBT_3" amino acids 45 to 122 (78 residues), 30.1 bits, see alignment E=7.3e-11 PF03061: 4HBT" amino acids 47 to 119 (73 residues), 49.5 bits, see alignment E=6.3e-17

Best Hits

Swiss-Prot: 38% identical to Y2264_ARCFU: Putative esterase AF_2264 (AF_2264) from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

KEGG orthology group: K02614, phenylacetic acid degradation protein (inferred from 100% identity to dvu:DVU0601)

Predicted SEED Role

"Phenylacetic acid degradation protein PaaD, thioesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72EH7 at UniProt or InterPro

Protein Sequence (144 amino acids)

>DVU0601 phenylacetic acid degradation protein PaaI (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTVERVRDFIMARDTFAQHLGMSLDEVREGFARATMPVDDRHRNGVGLVHGGAIFALADL
AFAAAANTSGVVSLSLTASISFLNAGRKGPLAAEAREISATKRIATYEVRVLDGEGTLLA
LCQATAYRKSHPIPEDDEEGKATS