Protein Info for DVU0495 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: conserved hypothetical protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF17785: PUA_3
  • amino acids 8 to 74 (67 residues), 59.3 bits, E=5.2e-20
• PF10672: Methyltrans_SAM
  • amino acids 175 to 349 (175 residues), 53.5 bits, E=4.2e-18
• PF03602: Cons_hypoth95
  • amino acids 221 to 303 (83 residues), 31.1 bits, E=3.7e-11
• PF05175: MTS
  • amino acids 223 to 349 (127 residues), 24.8 bits, E=3e-09

Best Hits

KEGG orthology group: K06969, ribosomal RNA large subunit methyltransferase I [EC: 2.1.1.-] (inferred from 99% identity to dvl:Dvul_2446)

Predicted SEED Role

"LSU m5C1962 methyltransferase RlmI" in subsystem Ribosome biogenesis bacterial

KEGG Metabolic Maps

• Alkaloid biosynthesis I
• Anthocyanin biosynthesis
• Benzoxazinone biosynthesis
• Biosynthesis of alkaloids derived from shikimate pathway
• Carotenoid biosynthesis - General
• Flavonoid biosynthesis
• Histidine metabolism
• Insect hormone biosynthesis
• Naphthalene and anthracene degradation
• Phenylpropanoid biosynthesis
• Porphyrin and chlorophyll metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

See Q72ES4 at UniProt or InterPro

Protein Sequence (398 amino acids)

>DVU0495 conserved hypothetical protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTPELKKLQLRRGEDRRLRVGHLWVFSNEVDVARTPLKDFAPGEAACVVDAGGRPLGTAY
VNPASLICARMVSRKPDAPLGPDLLRRRLTDALALRERLIGVPFYRLCFGEGDFLPGLVV
DRYGDVAAAQITTAGMEMHRDDIASVLQDMLSLSALLWRNDTASRELEGLPRVVETAFGA
VPETVTVEESGARFTAPLASGQKTGWFYDQRCNRIEAARFAQGARVLDAFCYLGSFGVMA
ARAGAVAVTFLDASRPALDAALANAAANATCETDAVHGDALDTLATLRDEGRRFEVVCID
PPAFIKRRKDVKQGLAAYQRVNELAIDLVADGGVLVTCSCSQHLDRDALRRVLLHAAGRR
RTQAQIVFQGHQGPDHPVHPAMPETDYLKCFIARVSRA