Protein Info for DVU0456 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: DHH family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF01368: DHH" amino acids 29 to 161 (133 residues), 29.4 bits, see alignment E=4.4e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvl:Dvul_2480)

Predicted SEED Role

"Kef-type K+ transport systems (NAD-binding component fused to domain related to exopolyphosphatase)" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72EW2 at UniProt or InterPro

Protein Sequence (335 amino acids)

>DVU0456 DHH family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSYFRKLDTKLPHLLELLNREERWLIVINADPDAMASAMALRRIMIHRVADVAIARVNEI
TRPDNLAMIRYLRIPMVKLTPTVAAQFDRFAVVDSQPHHHPLFRDLSFSLVIDHHPLSEK
NPVIADFKEIRTEYGSNSTIMTEFLYNMHIRPGQLLATALQFGIKTDTASFERAACDVDL
RAYRYLSKFSNPALLSRVARSEFRLHWLDYFSKAFISMHKCGSGQYVYVGEVENPDILVV
IADFFMRVHEIRWTAVCGVYQDTIVVIFRGDGVTRDLGRYASAQFSDIGSAGGHKAMARA
EIPLEKAAGRNVELFIFKKLLAPRKSARPREEAKP