Protein Info for DVU0441 in Desulfovibrio vulgaris Hildenborough JW710

Name: ade
Annotation: adenine deaminase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 TIGR01178: adenine deaminase" amino acids 21 to 572 (552 residues), 580.7 bits, see alignment E=1.4e-178 PF01979: Amidohydro_1" amino acids 67 to 350 (284 residues), 119.4 bits, see alignment E=3.2e-38 PF13382: Adenine_deam_C" amino acids 401 to 568 (168 residues), 202.9 bits, see alignment E=3.7e-64

Best Hits

Swiss-Prot: 100% identical to ADEC_DESVH: Adenine deaminase (ade) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K01486, adenine deaminase [EC: 3.5.4.2] (inferred from 100% identity to dvu:DVU0441)

Predicted SEED Role

"Adenine deaminase (EC 3.5.4.2)" in subsystem Purine conversions (EC 3.5.4.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72EX7 at UniProt or InterPro

Protein Sequence (575 amino acids)

>DVU0441 adenine deaminase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTYRPLLNDLVDMAAGRAPVDLVVRNARIVDVFSQRIVEAPLAIGGGRFLGFFEAEAHAT
LDAEGRYLLPGLIDGHVHIESSLVSPAQFARLVLARGTTAVIADPHEIANVCGLAGLRYM
LDATRDLPLDVRLALPSCVPATPFENAGAVLDAAALATLMDDPRVAGLGEMMNFPGVLAG
DADVLDKIALALDRGKTVDGHSPGLAGRDLATYAAARIATDHECTTVDEMHERIALGMYV
LLREGSAARDMARLAPGITPGNARRCVFCTDDRQPADILRDGHIDNHLRIAVSHGVDPVT
AVTIATLNAAECFGLRDRGAVAPGRVADFVLVDDLTGFAVRKVYAAGRLVARDGAVVVDL
PDHADPAVRDTVNIRPLDDTAFRLPLPTGLARVIGLQPHSLLTDALERDVPRDASGCFTP
GDGLVKLAVVERHKATGNVGVGIIEGYGLRGGAVATTVAHDSHNIVVAGDNDADMLVAVR
ELERTGGGITLCAGGRVLASLPLPVAGLMSDRPATEVSATFAQMLSIAHETLHISRDIEP
FMTLSFLTLPVIPALKLTDRGLFDVRTFSFTTVGV