Protein Info for DVU0256 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: ATP-dependent RNA helicase, DEAD/DEAH box family (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1121 PF00270: DEAD" amino acids 135 to 307 (173 residues), 101.7 bits, see alignment E=7.4e-33 PF00271: Helicase_C" amino acids 351 to 458 (108 residues), 49.9 bits, see alignment E=7.1e-17 PF09369: MZB" amino acids 719 to 798 (80 residues), 70.1 bits, see alignment 4.1e-23 PF13482: RNase_H_2" amino acids 995 to 1096 (102 residues), 22 bits, see alignment E=2.7e-08

Best Hits

KEGG orthology group: K06877, (no description) (inferred from 100% identity to dvu:DVU0256)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72FF8 at UniProt or InterPro

Protein Sequence (1121 amino acids)

>DVU0256 ATP-dependent RNA helicase, DEAD/DEAH box family (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MPHPQDGLDIVDNGPVVPRRDTALSGGLASGTLVADEVVGQHPAHDDTGRSLTQGSLLEP
PSHRPPSPLQDNEANASDLVAEYIAALLASRTFGRQVRHHRVIPQREAQTAPQHRPWTRA
VQDILTRQGIADLYSHQARATDIIRAGRDVVVATPTASGKTFIYNLPVLEQFLRDPDARA
IYLFPLKALAQDQLATFNALTAHWPRDARPAAAIYDGDTTDHFRRKIRNAPPPVLLTNPE
MLHLALLPHHEQWASLFASLTHVVVDEVHTYRGVLGAHMAQVFRRLRRVCERYGAQPSFV
FCSATVGNPGELAHNLTGLTPEVVTESGAPQGKRHFIFLDPEESPATAAIQLLRSALKRG
LRTIVYCQSRRMTELVSLWAAEKSGPYRDRISAYRAGFLPEERRDVEARMASGQLLAVIT
TSALELGIDIGSLDLCILVGYPGTVMSTLQRGGRVGRARQESAVVLVAGEDALDQYFMRH
PEDFFARGAEHAVLNPDNPVILARHLECAAAEIPLSAADPWLASPGASEAVQRLEREGLL
LRSADGSTLLASRKRPQRHVDLRGSGSTYTIEDGEGHIIGSVDGHRALRETHPGAVYLHR
GRTWVVQQLDPGARKVMASPARVGWYTRVRGNKQTEILDVQDRREAWGTRVFFGRLRVTE
TVTGYEKRSASGGRLLGVTPLDLPPTVFETEGLWFEIPDAAREATERELLHFMGSIHALE
HAAIGILPLLVMTDRNDLGGISTPMHPQVGRPAVFIYDGMPGGAALSRLAFARADELFAR
TRDAIGDCPCETGCPSCVHSPKCGSGNRPIDKAGALFLLDRMAAGTPERDDGPSLHAVMP
SDGVPLLPTEEHGVHDKQPEGAPPETARDGSRPAGDRGCIMPASYDAASISPSHPDDDTR
QENTMNATYTATTPDGVSVASSAMAPPEKASPASSCTVAAERKSAPRVMVLDVETRRSAA
EVGGWHRADRMGVSIAVLHDSGDDSFTAYPQDEVPAMLHRLREADLVVGFNIVRFDYTVL
SPFAPFDLHTLPTLDMLQKVKDRLSYRVSLDNLAQATLNAPKSADGLQALRWWQEGRLDL
IAEYCRKDVELTRDLYLYGLANGYLLFTNKAGQTVRVPVEW