Protein Info for DVU0071 in Desulfovibrio vulgaris Hildenborough JW710

Name: dinP
Annotation: DNA polymerase IV (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF00817: IMS" amino acids 3 to 150 (148 residues), 176.4 bits, see alignment E=5.4e-56 PF11798: IMS_HHH" amino acids 162 to 193 (32 residues), 30.2 bits, see alignment (E = 5.5e-11) PF11799: IMS_C" amino acids 236 to 343 (108 residues), 103.6 bits, see alignment E=1.2e-33

Best Hits

Swiss-Prot: 46% identical to DPO4_CALS4: DNA polymerase IV (dinB) from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)

KEGG orthology group: K02346, DNA polymerase IV [EC: 2.7.7.7] (inferred from 100% identity to dvl:Dvul_2890)

Predicted SEED Role

"DNA polymerase IV (EC 2.7.7.7)" in subsystem DNA repair, bacterial (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72FZ2 at UniProt or InterPro

Protein Sequence (386 amino acids)

>DVU0071 DNA polymerase IV (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MHIDMDAFFASVEQLDDPSLRGRPVIVGGSSERGVVSAASYEARRYGVRSAMPTVTARRL
CPHGVFVSGRRHRYAEVSRMVMAVLHDFSPVVEQASVDEAYLDATGLERLFGPVDEMAQR
LKGRVREATGGLTCSVGLAPVKFLAKIASDVNKPDGVFILPPEDVAAFLATLPVGRIPGV
GKRMLESLDLLGVRTAGDVLRHPVSFWERRFGKGGLVLYDRARGIDPRPLEPWTPPKSES
AEVTLAADTADRAVLRRWLLAQAERVGGSLRRQGLAGRTITLKVKYADFRQLTRSRTLPE
PVSATQTIFEEAWALLEALDLEAKVRLVGLGVSHFGGERQMSLPIGGMPRRDDTRRERLD
ATLDRLRARFGAGAVMRGDLVDFGDE