Protein Info for DVU3358 in Desulfovibrio vulgaris Hildenborough JW710

Name: parA
Annotation: ParA family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF10609: ParA" amino acids 15 to 263 (249 residues), 46.7 bits, see alignment E=9.7e-16 PF13614: AAA_31" amino acids 17 to 191 (175 residues), 213.4 bits, see alignment E=8.3e-67 PF09140: MipZ" amino acids 18 to 59 (42 residues), 22 bits, see alignment 3.2e-08 PF06564: CBP_BcsQ" amino acids 18 to 261 (244 residues), 38.6 bits, see alignment E=3.2e-13 PF01656: CbiA" amino acids 19 to 243 (225 residues), 102.4 bits, see alignment E=6e-33 PF00142: Fer4_NifH" amino acids 19 to 61 (43 residues), 37.7 bits, see alignment 6.1e-13 PF02374: ArsA_ATPase" amino acids 24 to 59 (36 residues), 31.5 bits, see alignment 4e-11

Best Hits

Swiss-Prot: 55% identical to SOJ_BACSU: Sporulation initiation inhibitor protein Soj (soj) from Bacillus subtilis (strain 168)

KEGG orthology group: K03496, chromosome partitioning protein (inferred from 100% identity to dvu:DVU3358)

Predicted SEED Role

"Chromosome (plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj" in subsystem Bacterial Cytoskeleton or Plasmid replication or Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q725R6 at UniProt or InterPro

Protein Sequence (276 amino acids)

>DVU3358 ParA family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MKLEVPHNATGTVVVARIIAIANQKGGVGKTTSSVNLAASLAIMEKKVLLVDCDPQANST
SGLGFDQEDIERSLYTSFFQPEEVVDAILTTSSPFLSLLPATTDLVAIELELVDKMAREY
YLADLLKPLDSRYDYILLDCPPSLGLITLNALCAARELLIPLQCEFFALEGIVKLLQTYE
QVKRRLNQNLSLLGVVLTMYDVRNKLSRQVKNEVRKCFPDHLFETVIPRNVRLSEAPSHG
KSIIHYDIKSKGAEAYLALAKEVVLRKPQRRDAQAG