Protein Info for DVU3351 in Desulfovibrio vulgaris Hildenborough JW710

Name: queA
Annotation: S-adenosylmethionine:tRNA ribosyltransferase-isomerase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 PF02547: Queuosine_synth" amino acids 13 to 370 (358 residues), 418.9 bits, see alignment E=7.1e-130 TIGR00113: S-adenosylmethionine:tRNA ribosyltransferase-isomerase" amino acids 120 to 370 (251 residues), 307.7 bits, see alignment E=4.8e-96

Best Hits

Swiss-Prot: 100% identical to QUEA_DESVH: S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queA) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K07568, S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC: 5.-.-.-] (inferred from 100% identity to dvl:Dvul_0043)

Predicted SEED Role

"S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.-.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.-.-.-

Use Curated BLAST to search for 5.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q725S3 at UniProt or InterPro

Protein Sequence (371 amino acids)

>DVU3351 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MKDDATGADFLLSGYDYELPEDRIAQHPPVERGLSRLLVLDRTTGERIHARFADLAEHLP
EGALLVANNSKVLPARLLGHRPTGGKVEFLLLTPLPLVTPLAAGPASGTVEPGWCVAEVE
GLLRASKPLRPGDTLSFGDDLRVEVVHKGEFGRSMVLLFWRGELATLFAREGHLPLPPYI
RRADGDEDRDRYQTVFAREDRLGSVAAPTAGLHFTPSLRETLTARGHQWAEVTLYVGYGT
FSPVRCADIRDHAMHREYVEVTAETVEVIRRAKADGRPVVAVGTTSCRVLEGVATAKGTL
EPYAGWTDIFMYPGYTFKVVDHLITNFHLPESSLLMLVSAFAGRERVLATYREAIEEGYR
FFSYGDAMLLR